Anesthetics (i.v and inhaled) Flashcards

1
Q

Nitrous oxide

A

Inhaled, gaseous anesthetic

  • Gas at room temp
  • Low solubility
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2
Q

Enflurane

A

Inhaled, volatile anesthetic

  • Liquid at room temp
  • SE: Nephrotoxic, seizures
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3
Q

Isoflurane

A

Inhaled, volatile anesthetic

- Liquid at room temp

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4
Q

Halothane

A

Inhaled, volatile anesthetics

  • Liquid at room temp
  • SE: Hepatotoxic
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5
Q

Treat malignant hyperthermia

A

Dantrolene

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6
Q

Propofol

A

Iv anesthetics - GABAa potentiation

  • Induction and maintenance
  • Lipophilic => CNS => rapid action
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7
Q

Etomidate

A

Iv anesthetics - GABAa potentiation

  • Induction
  • Cardiovascular stability
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8
Q

Ketamine

A

Iv anesthetics - NMDA inhibition

  • Induction
  • Dissociative anesthesia
  • Cardiovascular stimulation
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9
Q

Benzodiazepines (anesthetics)

A

Iv anesthetics

  • Perioperatively
  • Conscious sedation
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10
Q

Barbiturates (anesthetics)

A

Iv anesthetics

  • Induction
  • E.g Thiopental - ultra-short
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11
Q

Inhaled anesthetics volatile liquids - ethers

A
  • (Diethylether)
  • Enflurane
  • Isoflurane
  • Desflurane
  • Sevoflurane
  • Methoxyflurane
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12
Q

Inhaled anesthetics volatile liquids - halogenated hydrocarbons

A
  • Halothane
  • (Chloroform)
  • (Ethylchloride)
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13
Q

Inhaled anesthetics gases

A
  • Nitrous oxide

- Xenon

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14
Q

Intravenous anesthetics

A
  • Barbiturates (thiopental, thiomylal, methohexital)
  • Propofol, fospropofol
  • Ketamine
  • Etomidate
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15
Q

Iv anesthetics - sedative hypnotics

A
  • BZDs (midazolam, diazepam, lorazepam)

- Alpha2 agonists (dexmedetomidin, clonidine)

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16
Q

Iv anesthetics - opioid analgesics

A
  • Morphine
  • Fentanyl
  • Sufentonil
  • Alfentonil
  • Ramifentonil
17
Q

Inhaled anesthetics with low solubility (<0.5)

A
  • Desflurane

- Nitrous oxide

18
Q

Metabolites halothane

A

Liver oxidation => Trifluoroacetic acid

*If low O2 tension => chlorotrifluoroethyl (free radical)

19
Q

Iv anesthetics with short context-sensitive half-time

A
  • Propofol
  • Etomidate
  • Ketamine
20
Q

Neuroleptic anesthesia

A

Droperidol-fentanyl + N2O