animal models for drug development 1

Question 1

who described animals as automata

Answer 1

descartes

Question 2

who argued that only humans have minds

Answer 2

descartes

Question 3

who stated that animals act without mind

Answer 3

sherrington

Question 4

who stated that basic sensations parallel human sensations

Answer 4

wundt

Question 5

what are the 4 criteria for a good animal model

Answer 5

similarity of inducing conditions
similarity of the behavioural state
similarity of the underlying neurobiological mechanism
similarity of clinically effective treatments

Question 6

who identified the 4 criteria for validating animals models

Answer 6

mckinney

Question 7

what is clonidine used for

Answer 7

addiction

Question 8

how does BU224 act

Answer 8

antagonist for imidazoline receptor

Question 9

describe the eyesight of the wistar rat

Answer 9

poor eyesight

Question 10

who set up the wistan rat breeding colony

Answer 10

donaldson

Question 11

describe the eyesight of long-evans rats

Answer 11

good vision

Question 12

describe the eyesight of sprague dawley rats

Answer 12

poor eyesight

Question 13

what is the importance of double blind studies for human trials

Answer 13

reduces placebo
reduces subject and experimenter bias