Anitdepressants Flashcards

0
Q

Tricyclic

Block reuptake of norepinephrine and serotonin

‘feline’

A

Amitriptyline - Elavil
Imipramine - Tofranil

Do not admin with MAOIs or St. John’s wort

Avoid alcohol

Contraindicated with seizure disorder

SEs: sedation

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1
Q

SSRIs

Inhibits serotonin uptake

‘pram’ ‘ine’

A

Duloxetine - Cymbalta
Fluoxetine - Prozac
Sertraline - Zoloft
Escitalopram - Lexapro

Avoid alcohol

Monitor for serotonin syndrome in first 72 hr (agitation, confusion, hallucinations)

SEs: weight gain, sexual dysfunction, fatigue, drowsiness

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2
Q

MAOIs

Increases norepinephrine, dopamine, and serotonin by blocking MAO-A

A

Phenelzine - Nardil
Isocarboxazid
Tranylcypromine

Avoid tyramine and caution with antihypertensives

Contraindicated with SSRIs, tricyclics, HF, CVA, renal insufficiency

SEs: CNS stimulation, orthostatic hypotension, hypertensive crisis with tyramine and SSRIs and tricyclics

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