Anorectal Conditions Flashcards

1
Q

Rectal Anatomy Review
- levator ani
- Dentate Line
- Anal Crypts of Morgagni
- Columns of MOrgani
- internal sphoncter
- external sphicncter

A

Levator Ani: the major muscle of the pelvic floor; resonsible for structure and support of the rectum (not working = bowel and bladder issues)

weak peliv floor can lead to rectal and vaginal prolapse

Dentate Line: “Transition Zone” where above the line is mucosa and below the line is squamoud epithelium

Crypts & Columns of Morgani: where abcesses can form

Internal Sphincter: under autonomic control: abcess and fissures can form here

External Sphincter: under voluntary control; abcesses and fissures can form here too

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2
Q

the Anorectal Exam
- what do you do

when is a colposcope used

A

Anorectal Exam
- inspect
- palpate
- DRE always!!
- can do an anoscopy: to visualize internal

Colposcope: can be used to magnify and visulize the inside of the anus better

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3
Q

Anorectal Bleeding
- conditions to think
- how to do the exam

A

Conditions
- hemorrhoids
- fissures
- polyps
- diverticular disease
- IBD
- colorectal cancer!!!

Exam
- inspection
- DRE
- anoscopy
- no need for FOBT: work them up with the gross blood
colonoscopy!!

when to get a colonoscopy
- unexplained bleeding
- bleeding which continues despite treatment
- systemic signs (weight loss, IDA)
- age older than 40 (unless they had colonoscopy in last year)
- family history of colorectal cancer

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4
Q

Pruritus Ani (anal itching)
- conditions
- the do not miss conditions

A

most commonl due to hygeine or due to atopic derm with the itch-scratch cycle

Conditions (some)
- fissures
- incontinence
- caffeine
- abcess
- canidida
- STI
- chemo
- DM
- IBD
- topic irritants

DO NOT MISS
- perirectal abcess
- fistulua
- STIs
- Malignancy
- Systemic Disease ( aplastic anemia, DM, IBD, leukemia, lymphoma)

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5
Q

Anorectal Mass
- conditions
- evaluation

A

Conditions (mostly they are benign)
- condyloma (warts)
- abcess
- polyp
- rectal prolapse
- hemorrhoids
- anal cancer

Evaluation
- inspection
- DRE (if internal mass)
- anscopy
- can use colposcope if needed magnification

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6
Q

Anorectal Pains
- conditions
- evaluation

A

Conditions
- fissure
- abscess
- thorbosed external hemorrhoid
- proctitis
- perneal sepsis (foriners gangrene)
- proctalgia fugax (pain comes and goes)

Evaluation
- inspection (preinal and perineum)
- DRE
- Anoscopy
DRE and anoscopy may need to wait becuase of how bad pain is
- colonoscopy if the fissures visable are not midline (that triggers chrons)
- refer to surgery: deep absecces or fistula

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7
Q

Fecal Incontinence
Conditions
Evaluation

A

Conditions
- Overflow: usually due to an obstruction (only liquid can pass)
- Reserovir: dimished colonic or rectal capacity due to strictures, carring, or congenital issues
- structural or neurologic issues
- medication (laxiitives!)
- disk herniation in the sacral region
- vaginal devliery complications
- dementia

Evaluation
- inspection
- DRE (impaction or rectal toen dimminshed)
- anal manometry (rectal tone)
- colonoscopy (for mass or obstrcuction)
- US or MRI for sphincter defects
- MMI for dementia

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8
Q

Hemorrhoids
- Etiology
- causes
- symptoms (for the 2 kinds)

A

Etiology
most commoon benign anorectal bleeding cause
- venous drainage of the anus is altered, this increases the pressure on the veins & the tissue = dilation occurs ; leads to outgrowth of the mucosa from the wall as a result

Causes
- obesity (increased pressure on venous return)
- pregnancy
- chornic diarrhea
- anal intercourse
- cirrhosis wih ascites
- pelvic floor dysfunction
- low-fiber diet -> constipation - strain

Two Kinds of Hemorrhoids : Symptoms
External
- exisit below the dentate line
- painful!
- bleeding
- pruritus

Internal
- exisit above the dentate line
- painless (visceral innnervation) bleeding (streaks)
- prolapse/grape-like tissue
- soiling

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9
Q

Hemorrhoids
Grading
Treatment

Thrombosed Hemorrhoid

A

Grading
- Grade I: asymptomatic outgrowth of mucosa due to the venous plexus outgrowth
- Grade II: hemorrhoids prolapse but spontaneously reduces
- Grade III: heorrhoid prolapses and must be manualy reduced ; ithcy and soiling
- Grafe IV: heorrhoid prolapses and cannot be reduced

Treatment
Conservative Treatment
- high-fiber diet (to reduce need to strain)
- increased water intake
- warm water sitz bath
- stool softeners

Medical Treatment
- OTCs: astringets (witch hazel), corticosteroids and topical anestetics
- Rx: topical nitroglycerine or topical nifedipine

Surgical Managment
- Grade I-III: outpt. procedure
1. banding: (wrap it, falls off)
2. infared photocoagulation

  • if the above fails, or Grade IV
    1. surgical removal or the columns of the hemorrhoid
    2. reduce the tissue allowing for prolapse to occur
    3. minimize pain and complications

Thrombosed Hemmrrhoid
- extremely painful!
- need a hemorrhoidectomy in 72 hours for best outcomes
- incision and evacualtion of the clot if ^^cannot hapeen

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10
Q

Anal Fissures
Etiology
Symptoms
Diagnosis
Treatment

A

Etiology
- a thin tear in the anal tissue; due to straining, anal intercourse, low fiber diet, anal trauma or secondary to other diseases

Symptoms

Acute presenation (< 8 weeks) :
- painful; shards of glass
- bleeding after defication

Chronic Presentation ( > 8 weeks)
- sentinel skin tag seen along with tears (normally at the tip of the laceration)
- enlarged anal papilla
- multiple tears, or tears not in midline = think Chron’s Disease

Diagnosis
on exam…
- a tear in the mucosa from the dentate line to the anal verge (way distal) = seen on acute presentation
- internal examination (shouldnt be needed) but if so, sedate pt.

Treatment (most should resolve spontaneously)
- fiber & fluid intake to soften stool
- sitz bath
- topical nitroglycerin or nifedipine

surgical intervention: if emdical management not effective after 8-12 weeks

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11
Q

Perirectal Abscess
- Etiology
- locations of abscess
- Symptoms
- Diagnosis
- Treatment

A

Etiology
- painful swelling within the rectal area (usually infected)

Symptoms
- pain is worse with defication, sitting or pressure on the abscess

Location of Abscess
- Perianal: the abscess around the anal verge (most distla opening of the anus)
- Ischiorectal/ischioanal: on the bottck
- intersphincteric: no changes to the skin, mass is protruding into the rectum interally
- Supralevator absess: SEVERE PAIN, fever, urinary retention, suppartion above the anal ring & minial PE findings; see on CT or US

Diagnosis
on exam….
- erythema
- pain
- induration
- mass

Treatment
- if perianal: I & D
- if anywhere else: surgery
- everyone gets emperic anx: amox.-clav. or cipro + metronidazole

risk of fistual (50%) or sepsis

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12
Q

Fistula in Ano
- Etiology
- Symptoms

A

Etiology
- most commonly a result of an abscess complications : the abscess ruptures when drained & the epithelialized tract forms connections to abscess to other areas of perianal skin

other cuases (if not an abscess)
- Chron’s
- Obstetric trauma
- radiation proctitis (due to infection)
- rectal foregin body
- infection: lymphogranuloma venerum (due to chalymida)
- malingnancy

Symptoms
- pain
- mild bleeding
- discharge (watery, blood-tinged)
- on exam: see the draining sinus tracking

Diagnosis
- see the sinuses on exam
- still need imaging: MRI with and without contrast
- endoscopic US can also be done
- (do not do CT – wont see it)

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13
Q

Fistula in Ano
Treatment
what makes it a complicated fistula

A

Complicated Fistula
- vaginal anterior tracking
- multipel tracts
- recurrent fistual forming
- extrasphincteric
- proximal to the dentate line (traveling up)
- related to IBD
- related to HIV or TB
- local radiation

Treatment (only exploration under sedation can determine if it is simple or complex)

Conservative (for simple)
- sitz baths
- high fiber diet
- analgesics

Surgery (fistulotomy)
- complex
- non healting
- multiple risk factors for a complex to form
- surgery goal is to preserve fecal continence

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14
Q

Pilonidal Disease
Etiology
Symptoms
Diagnosis
treatment

A

Etiology
- an infection of skin and subcutaneous tissue at or near the upper part of the natal cleft
- not a “true cyst” since there is not epithelial lining : but the cavity contains debris and liklely to be infected

Risk Factors for Infection
- obeseity
- prolonged sedintary lifestlye/sititng
- trauma/irritation
- deep cleft
- family hx.

Symptoms
- can be asymptomatic
- chronically draining
- abscessed: fever, redness, pain, mass

Treatment
- if asymptomatic without signs of infection: observe
- if abscessed: I&D
- if recurrent: surgical excision

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15
Q

Procidentia (Rectal Prolapse)
Etiology
Symptoms

A

Etiology
- a circumferentail full thickness protrusion of the rectum through the anal sphincters

Risk Factors for Rectal Prolaspe
- age > 60
- female with pelvic floor dysfunction
- cystic fiberosis
- connective tissue disorder
- congenital hypothyroidism
- hirshsprung disease ( constipation related strain = prolapse)
- dementia

procidentia: full thickness of the colon to prolapse = see conccentric circles

mucosal prolapse: just the mucosal layer prolasping: see more of folds radiating

Symptoms
- mass: often with or after defecation
- constipation & straining = leads to the prolapse
- incontinence
- rectal bleeding
- por hygeine

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16
Q

Procidentia (Rectal Prolapse)
Diagnosis
Treatment

A

Diagnosis
- usually clincal, the tests will come after it has been pushed back
- cystoproctography (pelvic flood muscle dysfunction test)
- colonscopy
- sitzmark study (colonic inertia- no movement)

Treatment
- a manual reduction
- bulk forming agents to reduce need to strain
- surgery is the definintive

17
Q

Condyloma Acuminata (anal warts)
Etiology
Symptoms
Diagnosis
Treatment

A

Etiology
- HPV: strains 6 & 11 (the non oncogenic strains)
- transmitted: auto-innoculation or ano-receptive intercourse

Symptoms
- warts/lesions may be on the outside (external) or internal, just distal to the dentate line
- cauliflower-like grey or pink growth lesions
- 1-5 mm in size; can be a singular lesion or multiple

Diagnosis
- a clinical diagnosis no labs needed
- can do an acetic acid exam under microscopy to see the oncogenic strains (?) (because co-infection is common)

Treatment
- Trichloroacetic acid cheap & effective
- cryotherapy
- imiquimod
- podofilox
- laser
- interferon
- 5FU

18
Q

Anal syphilis
Etiology
Symptoms
Diagnosis
Treatment

A

Etiology
- treponema pallidum infection
- usually a result of anal intercourse

Symptoms
- can be asymptomatic
- primary syphili = painless chancre, lymphadenopathy
- secondary syphilis = condyloma lata (warts), secreting foul smelling mucous

Diagnosis
- seologic tesing

Treatment
- penicillin

19
Q

Proctitis
Etiology
Symptoms
Diagnosis
Treatment

A

Etiology

  • a variety of STIs cause an infection in the rectum
  • c. trachomatis, gonorrhea, syphilils, HSV
  • other non-STI pathogens too: camplybacter, giardia, shigella, entameoba histolytical
  • HIV + pt: think og MCV, MAC, salmonella & cryposporidum

Symptoms
- can be infectious or just inflammaed (oral-anal and anal intercourse)
- rectal pain & fullness
- discharge
- bleeding
- left sided abd. pain (right before the rectum)

Diagnosis
- anoscopy
- anal smear & culutre

Treatment
- emperic: ceftriaxone & doxycycline
- then tailor to your culutres

20
Q

Proctitis: specific to HSV
- specific symptoms and signs
- treatment

A

HSV: common cause of proctitis in those who have anal intercourse (receptive)

Symptoms
- rectal fullness
- radicular pain (if the lumbar/sacarl nerves involved)
- itching
- constipation/tenesmus
- urianry retention

Signs
- small, grouper vesilces in the perianal and anal tissue

if sigmoidoscopy done (not needed) would see rectal uclers

Treatment
- acyclovir, famciclovir or valacyclovir

21
Q

Radiation Proctitis
- Acute v Chronic endoscopic findings
- Treatment

A

proctitis (inflammation) as a result of radiation within the area
- like for other cancers

Acute: Endoscopy findings
- pallor of th emucosa
- friability of mucosa
- telangiestasis ( spidery like web vessels)
- skip lesions (normal – area of issues —- normal)

Chronic: Endoscopy findings
- pale mucosa; noncompliant
- mucosal hemorrhage
- telangiectasias
- strictures, ulcerations & fistulas due to the scarring over time

Treatment
- enemas with Sucrulfate (protective for mucosa)
- can use hydrocortisone enema
- fiber & stool softened
- can abalte lesions with endoscopic treatment
- surgery if stricutre, obstructions or perforations

22
Q

Anal Dysplasia & Anal Cancer
- Etiology
- Symptoms
- those at an increased risk

A

Etiology
- HPV 16 & 18
- commonly in those who are immunosuppressed

SYmptoms
- painless rectal bleeding
- palpable mass on DRE
- ulcers
- polyps
- verrucous growths (HSV)
- fullness, discharge
- pencil thin stools sliding past the mass

Risk Factors:
- MSM (receptive anal intercourse)
- immunosuppresed
- IVDU
- increase sex partenrs/ high risk sex
- somker
- chronic inflammation (fissures, abscesses & IBD)
- lichen sclerosis
- genital warts hx.
- cervical cancer CIN, vulvuar CA or penile CA

23
Q

Anal Dysplasia/Cancer
Diagnosis
Treatment

A

Diagnosis
- pap smear for screening and diagnosis (pap of the rectum!!) for those…
1. histoyr of HPV infection in anogentials
2. anal receptive intercourse
3. mutliple sex partners
4. hisory of STI or anal condyloma

Treatment
- if Dysplasia: topicl or ablasive treatment (cryo, laser, 5-FU)
- if cancer
1. combo external beam radiation + 5-FU and mitomycin C
2. surgery if tumor is residual
3. PDL-I for recurrent disease

24
Q

Fecal Impaction
- Etiology
- Risk Factors
- Symptoms
- Treatment

A

Etiology
- a collection of dry, hard stool in the distal rectum
Risk Factors
- older age
- opioid use!!!!!!
- neurologica disease
- low fiber
- hypothyroid

Symptoms
- constipation
- overflow diarrhea (only liquid can pass)
- hard fecal mass palpable on DRE

Treatment
- manual disimpaction
- warm water mineral oil enema
- once removed: can use mirolax to move rest through

significant tenderness may be a sign of performation or ischemia