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FARMAKOLOGIJA ISPIT > ANS > Flashcards

ANS Flashcards

(14 cards)

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1
Q

Struktura lokalnih anestetika

A

Estarska i amidna struktura

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2
Q

Lokalni anestetici sa estarskom strukturom

A

KOKAIN
BENZOKAIN
PROKAIN
TETRAKAIN

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3
Q

Neželjena dejstva lokalnih anestetika

A

-posledica apsorbcije toksične količine leka
-ako se resorbuje ima najviše efekata na CNS I KVS

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4
Q

Neželjena dejstva LA na CNS

A

-inhibicija inhibitornih puteva => prekomerna ekscitacija
-blokiranje ekscitativnih puteva =>depresija CNS
konvulzije, smrt

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5
Q

Gde se ne smeju primenjivati lokalni anestetici

A

u inficirana područja

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6
Q

Vrste Lokalnih anestezija

A

-površinska
-epiduralna
-infiltraciona
-spinalna (subarahnoidalna)
-regionalna

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7
Q

Antihistaminici druge generacije

A

CETIRIZIN
LEVOCITIRIZIN
LORATADIN
DESLORATADIN
-ne prolaze HE barijeru, nema sedacije
urtikarije i alergije
-ne koriste se kod kinetoza i kao antiemetička sredstva

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8
Q

Indikacije za antihistaminike

A

-alergije
-kinetoze
-svrab
-lokalna anestezija

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9
Q

Šta dajemo kod anafilaktičkog šoka

A

-adrenalin
-kiseonik
-fiziološki rastvor
-H1 antihistaminici
-glukokortikoidi
-beta 2 adrenergički agonisti

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10
Q

H1 receptori

A

endote
glatki mišići
CNS
-Gq

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11
Q

Aktivacija H1 receptora

A

bronhokonstrikcija, vazodilatacija
treosetljivost tip 1
stimulišu receptore za bol i svrab

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12
Q

Neželjena dejstva antihistaminika

A

-pospanost i sedacija
-antimuskarinski efekat
-ortostatska hipotenzija
-interakcije sa drugim lekovima

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13
Q

H2 receptori

A

mukoza želuca i srce
Gs
stimulacija rada srca i sekrecija HCl u parijentalnim žlezdama

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14
Q

Površinska anestezija

A

-površina sluznica
-tetrakain i benzokain

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FARMAKOLOGIJA ISPIT (3 decks)

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