ANS DRUGS Flashcards
(27 cards)
Atropine
muscarinic antagonist
for poisoning with AchE Is
Isoproterenol
direct sympathomimetic
beta agonist
beta 1 = beta 2
increase heart contractility, bronchodilation
Atenolol
selective beta 1 antagonist
decrase contractility of the heart
Ipratroprium
inhaled muscarinic antagonist
for irreversible AchE I posoning - effects in lungs!
Metoprolol
selective beta 1 antagonist
decrase contractility of the heart
Prazosin
alpha 1 antagonist (sympathetic)
vascular dilation
Albuterol
direct sympathomimetic
beta 2 agonist
bronchodilation
Sarin
WARFARE AGENT - ORGANOPHOSPHATE
cholinesterase inhibitor - irreversible!
Phentolamine
alpha adrenergic antagonist
non-selective
vasodilation, GI muscle relaxation
Amphetamine
indirect sympathomimetic
alpha + beta effects
Carvedilol
beta and alpha antagonist
decrease contractility of the heart, vasodilation
Norepinephrine
direct sympathomimetic
non-selective alpha and beta
alpha > beta1 > beta2
vasodilation, heart contractility, bronchorelaxation
Pyridostigmine
cholinesterase inhibitor
peripherally active only
spontaneously reversible
Dopamine
beta agonist –> alpha agonist
heart contractility –> vasoconstriction
Clonodine
alpha 2 agonist (central)
contraction of GI sphincters + NE negative feedback in pre-syn adrenergic neurons
propranalol
non-selective beta antagonist
sympathetic
decrease contractility of the heart, constriction of bronchioles + GI
Topicamide
ocular muscarinic antagonist
cocaine
indirect sympathomimetic
alpha and beta agonist
Dobutamine
direct sympathomimetic
beta 1 agonist
increase heart contractility
Pilocarpine
Muscarinic receptor agonist
parasympathetic
2PAM
Cholinesterase Reactivator
When AchE has been irreversibly inactivated
Labetatol
beta and alpha antagonist
decrease contractility of the heart, vasodilation
malathion
PESTICIDE - ORGANOPHOSPHATE
cholinesterase inhibitor - irreversible!
Phenylephrine
alpha 1 agonist (direct!)
vasoconstriction
