Antenatal care

Question 1

What should women be informed about the additional risk of miscarriage following amniocentesis or CVS?

Answer 1

It is likely to be below 0.5%

Question 2

What is the earliest gestation amniocentesis should be performed?

Answer 2

15 weeks gestation

Question 3

What is the earliest gestation CVS should be performed?

Answer 3

10 weeks gestation

Question 4

What should women be informed about the additional miscarriage risk for twin pregnancy following amniocentesis or CVS?

Answer 4

The additional risk is around 1%

Question 5

What gestation is CVS usually performed between?

Answer 5

11+0 and 13+6 weeks gestation

Question 6

1-2% of all CVS results will be affected by which confounding complication?

Answer 6

Combined placental mosaicism

Question 7

RCOG recommends those trained in CVS and Amniocentesis should carry out how many of these procedure per year as a minimum to maintain skills?

Answer 7

20

Question 8

Aside from miscarriage, what other risk is increased if amniocentesis is carried out prior to 15 weeks gestation?

Answer 8

Talipes equinovarus

Question 9

What risks are increased with CVS before 10 weeks?

Answer 9

Oromandibular and limb defects

Question 10

What complication is increased when amniocentesis is carried out in the third trimester?

Answer 10

Culture failure

Question 11

Corticosteroids should be offered to women between which gestations when imminent preterm birth is anticipated?

Answer 11

24+0 - 34+6 weeks

Question 12

What are the two potential harmful side effects of antenatal corticosteroids for the neonate?

Answer 12

Neonatal hypoglycaemia and developmental delay

Question 13

What is the number needed to treat to prevent 1 neonatal death by giving antenatal corticosteroids between 22-34+6 weeks gestation?

Answer 13

38.5

Question 14

How should women with multiple pregnancy be counselled about the use of antenatal corticosteroids?

Answer 14

In line with the guidance for singleton pregnancy, however they should be advised of the uncertainties around their use in multiple pregnancy

Question 15

What is the median latency of delivery after PPROM ?

Answer 15

7 days

Question 16

What is the change in blood oxygen saturation during a flight at cruising altitude?

Answer 16

SpO2 reduced by 10%

Question 17

What does the evidence show about risk of adverse pregnancy events with air travel?

Answer 17

There is no good data to suggest an increase in preterm labour, PPROM or abruption

Question 18

What advice should be given to women about the maximum gestation to fly at?

Answer 18

36 weeks if no complications
32 weeks if any risk factors for preterm birth

Question 19

Which conditions are absolute contraindications to air flight?

Answer 19

Anaemia with Hb <75
Recent haemorrhage
Otitis media or sinusitis
Serious cardiac or respiratory disease
Recent sickle cell crisis
Recent GI surgery
A fracture

Question 20

What advice should be given to pregnant women about antimalarial therapy?

Answer 20

Anti-malarials are safe in pregnancy

Question 21

Which travel vaccines should be avoided in pregnant women?

Answer 21

Live vaccines such as the Yellow Fever vaccine

Question 22

What percentage of babies born in the UK weigh more than 4,000g?

Answer 22

10%

Question 23

What is the Number Needed to Treat to prevent 1 fracture by using IOL in LGA?

Answer 23

60