What are the 2 common classifications of nitrodilators?
What are the names of some common short-acting nitrates?
Sublingual nitroglycerin (Nitrostat) Nitroglycerin Spray (NitroMist)
What are the names of some common long-acting nitrates?
Isosorbide dinitrate (Isordil)
Which drug is commonly prescribed for Pt.’s with stable angina?
Sublingual nitroglycerin (short-acting)
Form nitric oxide, which leads to smooth muscle relaxation (vasodilation) - prescribed to keep vessels open for as long as possible so that BF is not occluded
Decrease TPR ==> decrease SVR ==> decrease BP ==> decrease stress on heart
Common adverse reactions:
OTN (if vessels overdilated)
need to monitor BP response if Pt. takes it in the clinic bc of chest pain