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MK JR Pharmacology Summary > Anti-anginals > Flashcards

Anti-anginals Flashcards

1
Q

List two nitrates

A

Gycerly trinitrate, isosorbide dinitrate, isosorbide 5-mononitrate

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2
Q

Mechanism of nitrates as anti-anginals

A

Vascular smooth muscle relaxation, venodilatation > arteriolar dilatation

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3
Q

What class of drug is Nicorandil?

A

K+ Channel opener

used in treatment ischaemic heart disease

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4
Q

Mechanism of Nicorandil

A

K+ Channel opener
used in treatment ischaemic heart disease, anti-anginal

Arteriolar dilator. Activates mitochondrial K+ATP channels and a NO donor acting via NO/soluble guanylyl cyclase (sGC)-dependent mechanism

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MK JR Pharmacology Summary (22 decks)

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