Anti-epileptics

Question 1

What are the side effects of phenytoin?

Answer 1

P 450 inducer
H irsutism
E nlarged gums
N ystagmus
Y ellow-browning of the skin
T eratogenic
O steomalacia
I nhibition of folate metabolism
N europathies: ataxia, headache, vertigo

Question 2

What are the side effects of sodium valproate?

Answer 2

V omiting/nausea
A norexia
L iver toxicity
P ancreatitis
R etention of weight
O edema
A lopecia
T eratogenic/tremor
E nzyme inhibition

Question 3

Which AEDs are safe to use in epileptic pregnant women?

Answer 3

Lamotrigine

Levetiracetam