Anti-epileptics Flashcards
(4 cards)
1
Q
Benzodiazepines
A
Bints post synaptic GABA ligand gated CHLORIDE channels
Increases chloride causing hyperpolarisation and stabelisation
2
Q
TCAs
A
Block serotonin and norepinephrine reuptake increase NT concentrations
3
Q
Phenytoin
A
non specific sodium channel blocker
primary site of action is in the motor cortex
used in status
4
Q
Sodium valproate
A
Enhances GABA inhibition by increasing GABA concentrations and blocking SODIUM channels