Anti-hyperglycemic Flashcards
(33 cards)
What are oral anti-hyperglycemic agents?
Medications used to lower blood glucose levels in individuals with type 2 diabetes.
True or False: Oral anti-hyperglycemic agents are used for type 1 diabetes.
False
Name one class of oral anti-hyperglycemic agents.
Sulfonylureas
What is the primary mechanism of action for biguanides?
To decrease hepatic glucose production and improve insulin sensitivity.
Fill in the blank: Metformin is a type of __________.
biguanide
Which oral anti-hyperglycemic agent stimulates insulin secretion from the pancreas?
Sulfonylureas
What are DPP-4 inhibitors known for?
They inhibit the enzyme dipeptidyl peptidase-4, which increases incretin levels.
True or False: Thiazolidinediones increase insulin sensitivity in peripheral tissues.
True
What is the brand name of the DPP-4 inhibitor sitagliptin?
Januvia
Name a side effect associated with sulfonylureas.
Hypoglycemia
Fill in the blank: __________ are medications that delay carbohydrate absorption in the intestines.
Alpha-glucosidase inhibitors
What is the primary benefit of using GLP-1 receptor agonists?
They promote weight loss and improve glycemic control.
Which oral anti-hyperglycemic agent is a sodium-glucose co-transporter-2 (SGLT2) inhibitor?
Canagliflozin
What is the mechanism of action for SGLT2 inhibitors?
They reduce glucose reabsorption in the kidneys.
True or False: All oral anti-hyperglycemic agents are taken once a day.
False
What is the starting dose of Metformin usually prescribed?
500 mg
Fill in the blank: __________ is a common side effect of Metformin.
Gastrointestinal upset
Which class of drugs is known to cause weight gain?
Sulfonylureas
What is the target HbA1c level for most adults with diabetes?
Less than 7%
True or False: Thiazolidinediones can increase the risk of heart failure.
True
What is the role of insulin sensitizers?
To enhance the body’s response to insulin.
Name a contraindication for using Metformin.
Severe renal impairment
What are incretin mimetics?
Drugs that mimic the action of incretin hormones to lower blood sugar.
Fill in the blank: The mechanism of action for DPP-4 inhibitors involves __________.
inhibition of the DPP-4 enzyme