Anti-hyperglycemic Flashcards

(33 cards)

1
Q

What are oral anti-hyperglycemic agents?

A

Medications used to lower blood glucose levels in individuals with type 2 diabetes.

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2
Q

True or False: Oral anti-hyperglycemic agents are used for type 1 diabetes.

A

False

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3
Q

Name one class of oral anti-hyperglycemic agents.

A

Sulfonylureas

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4
Q

What is the primary mechanism of action for biguanides?

A

To decrease hepatic glucose production and improve insulin sensitivity.

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5
Q

Fill in the blank: Metformin is a type of __________.

A

biguanide

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6
Q

Which oral anti-hyperglycemic agent stimulates insulin secretion from the pancreas?

A

Sulfonylureas

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7
Q

What are DPP-4 inhibitors known for?

A

They inhibit the enzyme dipeptidyl peptidase-4, which increases incretin levels.

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8
Q

True or False: Thiazolidinediones increase insulin sensitivity in peripheral tissues.

A

True

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9
Q

What is the brand name of the DPP-4 inhibitor sitagliptin?

A

Januvia

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10
Q

Name a side effect associated with sulfonylureas.

A

Hypoglycemia

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11
Q

Fill in the blank: __________ are medications that delay carbohydrate absorption in the intestines.

A

Alpha-glucosidase inhibitors

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12
Q

What is the primary benefit of using GLP-1 receptor agonists?

A

They promote weight loss and improve glycemic control.

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13
Q

Which oral anti-hyperglycemic agent is a sodium-glucose co-transporter-2 (SGLT2) inhibitor?

A

Canagliflozin

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14
Q

What is the mechanism of action for SGLT2 inhibitors?

A

They reduce glucose reabsorption in the kidneys.

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15
Q

True or False: All oral anti-hyperglycemic agents are taken once a day.

A

False

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16
Q

What is the starting dose of Metformin usually prescribed?

17
Q

Fill in the blank: __________ is a common side effect of Metformin.

A

Gastrointestinal upset

18
Q

Which class of drugs is known to cause weight gain?

A

Sulfonylureas

19
Q

What is the target HbA1c level for most adults with diabetes?

20
Q

True or False: Thiazolidinediones can increase the risk of heart failure.

21
Q

What is the role of insulin sensitizers?

A

To enhance the body’s response to insulin.

22
Q

Name a contraindication for using Metformin.

A

Severe renal impairment

23
Q

What are incretin mimetics?

A

Drugs that mimic the action of incretin hormones to lower blood sugar.

24
Q

Fill in the blank: The mechanism of action for DPP-4 inhibitors involves __________.

A

inhibition of the DPP-4 enzyme

25
What is the main advantage of SGLT2 inhibitors?
They promote renal excretion of glucose.
26
True or False: All oral anti-hyperglycemic agents must be used in combination with insulin.
False
27
What is the typical response time for oral anti-hyperglycemic agents?
They typically take weeks to show full effects.
28
Which agent is used to treat hypoglycemia caused by sulfonylureas?
Glucagon
29
What is a common monitoring parameter for patients on oral anti-hyperglycemic agents?
Blood glucose levels
30
Fill in the blank: __________ is a potential side effect of SGLT2 inhibitors.
Urinary tract infections
31
What is the main goal of therapy with oral anti-hyperglycemic agents?
To achieve and maintain good glycemic control.
32
True or False: Lifestyle changes are not important when using oral anti-hyperglycemic agents.
False
33
What is the importance of patient education when prescribing oral anti-hyperglycemic agents?
To ensure proper use and adherence to therapy.