ANTI INFLAMATORY DRUGS

Question 1

class of medications designed specifically to relieve pain

Answer 1

analgesics

Question 2

which analgesic need prescription

Answer 2

opioids or narcotics

Question 3

Response to tissue injury and infection

Other causes: trauma, surgical interventions, extreme hot and cold, and caustic chemical agents.

Answer 3

Inflammation

Question 4

Protective mechanism

Answer 4

Inflammation

Question 5

if there is an tissue injury it causes an __________

Answer 5

vasoconstriction

Question 6

if there is a tissue injury, and released chemical mediators it causes vasodilation and leads to ___________

Answer 6

redness. erythema

Question 7

if there is a tissue injury, and released chemical mediators it causes increase permeability that causes

Answer 7

swelling, edema

Question 8

if there is a tissue injury, and released chemical mediators it causes pain

Answer 8

true

Question 9

if there is a tissue injury, and released chemical mediators it causes fever

Answer 9

true

Question 10

redness, erythema, selling, edema, pain, heat leads to __________

Answer 10

loss of function

Question 11

it is the enzyme responsible for conversion of arachidonic acid into prostaglandins

Answer 11

Cyclooxygenase (Cox)

Question 12

what is the function of cox 1

Answer 12

-Protects stomach lining

-Regulates blood platelets

Question 13

what is the function of cox 2

Answer 13

Triggers inflammation and pain

Question 14

under anti inflammatory that relieves pain

Answer 14

analgesic

Question 15

it is under anti inflammatory that reduce elevated body temperature

Answer 15

antipyretic

Question 16

it is under anti inflammatory that inhibits platelet aggregation

Answer 16

anticoagulant

Question 17

give the seven groups of NSAIDs

Answer 17

Salicylates

Para- Chlorobenzoic acid

Phenylacetic acid

Propionic acid derivatives

Fenamates

Oxicams

Selective Cox-2 Inhibitors

Question 18

other names for Para-chlorobenzoic Acid

Answer 18

indoles

Question 19

what group of NSAIDs aspirin belongs to

Answer 19

salicylates

Question 20

what is the other name for aspirin

Answer 20

Triggers inflammation and pain

Question 21

what are the functions of aspirin

Answer 21

-Anti-inflammatory
-antiplatelet
-antipyretic effects

Question 22

Therapeutic serum salicylate level

Answer 22

10- 30 mg/dl

Question 23

Toxic serum salicylate level

Answer 23

> 40–50 mg/dl

Question 24

Hypersensitivity to salicylate products

Answer 24

tinnitus, vertigo, bronchospasm

Question 25

contraindication of salicylates

Answer 25

pregnancy

Question 26

why salicylates should not be taken by children with flu symptoms

Answer 26

it cause reye syndrome

Question 27

what damage it causes in the body by reye syndrome

Answer 27

liver damage and encephalopathy

Question 28

why salicylates should be taken with milk, water, or food

Answer 28

it causes GI Upset

Question 29

give examples of drug under para-chlorobenzoic acid

Answer 29

indomethacin and sulindac

Question 30

give brand name under indomethacin

Answer 30

Indocin

Question 31

give brand name under sulindac

Answer 31

Clinoril

Question 32

para-chlorobenzoic acid indication

Answer 32

Rheumatoid arthritis Gouty arthritis Osteoarthritis

Question 33

side effects of para-chlorobenzoic acid

Answer 33

Increased BP, sodium and water retention

Question 34

drugs under phenyalcetic acid derivative

Answer 34

Diclofenac Na and Ketorolac

Question 35

Brand name under Diclofenac Na

Answer 35

Volataren

Question 36

Phenylacetic acid indications

Answer 36

Rheumatoid Arthritis Osteoarthritis Ankylosing spondylitis

Question 37

what is the function of ketorolac

Answer 37

short term management of pain

Question 38

what is the first injectable NSAIDs

Answer 38

Ketorolac

Question 39

ketorolac is short term but have greater analgesic effect

Answer 39

true

Question 40

when ketorolac may be given and who is the patient

Answer 40

1st 24hrs to post op patients

Question 41

drug under propionic acid

Answer 41

ibuprofens

Question 42

brand name under ibuprofens

Answer 42

Alaxan, Advil, and Medicol

Question 43

ibuprofen drug interactions

Answer 43

increase effects of -warfarin -sulfonamides -certain cephalosporin -phenytoin -insulin -oral hypoglycemic

Question 44

what side effects of propionic acid cause

Answer 44

gastric upset

Question 45

indication of Fenamates

Answer 45

Acute and Chronic arthritic

Question 45

SE OF Fenamates

Answer 45

Gastric irritation

Question 45

contraindication of Fenamates

Answer 45

patient with peptic ulcer

Question 45

drugs under fenamtes

Answer 45

Mefenamic Acid and Meclofenamate Na Monohydrate

Question 46

brand name under mefenamic acid

Answer 46

Ponstel and Ponstan

Question 47

Brand name under meclofenamate Na Monohydrate

Answer 47

Meclomen

Question 48

Indication of Oxicams

Answer 48

Long term arthritic conditions

Question 49

SE of oxicams

Answer 49

lower incidence of gastric problems, ulceration, epigastric distress

Question 50

what other drugs oxicam should not be taken with

Answer 50

aspirin and other NSAIDS

Question 51

drugs under oxicams

Answer 51

piroxicam and meloxicam

Question 52

brand name under piroxicam

Answer 52

Feldene flash

Question 53

what are the drugs under cox 2 inhibitors

Answer 53

Celecoxib, Rofecoxib, and Nabumetone

Question 54

brand name under celecoxib

Answer 54

celebrex

Question 55

brand name under Rofecoxib

Answer 55

Vioxx

Question 56

brand name under Nabutemone

Answer 56

Relafen

Question 57

nursing considerations in Cox 2 inhibitors

Answer 57

-should not be taken during third trimester of pregnancy -NSAIDs in elderly -assessment of renal function -prescribe dose may need to be decreased

Question 58

Suppressing and preventing many of the components of the inflammatory process at the injured site

Answer 58

corticosteroids

Question 59

drugs under corticosteroids

Answer 59

Dexamethasone Prednisone Prednisolone

Question 60

it is for the Inflammation of the joints and Uric Acid

Answer 60

antigout drugs

Question 61

3 segments under the antigout drugs

Answer 61

colchicine, uric acid inhibitor, uricosurics

Question 62

what is the function of colchicine

Answer 62

inhibit leukocytes on the inflamed site

Question 63

SE of Colchicine

Answer 63

gastric irritation, NV, diarrhea, abdominal pain

Question 64

drugs under uric acid inhibitor

Answer 64

allopurinol and thiazide diuretics

Question 65

what is the function of allopurinol

Answer 65

Inhibit final steps of uric acid synthesis

Question 66

allopurinol indication

Answer 66

gout patients with renal impairment

Question 67

considerations when taking allopurinol

Answer 67

no caffeine and alcohol

Question 68

what is the function of thiazide diuretics

Answer 68

Increase level of uric acid

Question 69

what is the function of uricosuric

Answer 69

Alleviating chronic gout

Question 70

drug under uricosurics

Answer 70

probenecid

Question 71

what id the function of probenecid

Answer 71

Increase rate of uric acid excretions in the kidneys

Question 72

SE of probenecid

Answer 72

Sore gums, headache, flushed skin