Anti- Malarials Flashcards Preview

PHARMACOLOGY > Anti- Malarials > Flashcards

Flashcards in Anti- Malarials Deck (27):
1

Three potential ways to control malaria

Vector control
Drug therapy
Vaccination

2

(4) other names of Malaria

Intermittent fever
The fever
Marsh fever
Ague

3

Break bone fever

DENGUE

4

Classification of Anti- Malarial Drugs

Cinchona Alkaloids
4- Aminoquinolines
8- Aminoquinolines
Polycyclic anti malarial drugs
Fixed combination

5

Clinical manifestations of Malaria

fever, chills, and flu-like illness.

6

Quinine Sulfate indications

1. Nocturnal leg cramps
2. Chloroquine resistant P. falciparum strain

7

Quinine Sulfate side effect

Abortifacient

8

Lethal for all Plasmodium schizonts and gametocytes from P. vivax and P. malariae

Quinine Sulfate

9

Potent antimalarial but is primary indicated for cardiac arrythmias

Quinidine

10

Chloroquine (Aralen)

Prophylaxis and treatment of malaria
DOC for erthyrocytic stage of falciparum malaria

11

Amiodarone (Cardorone)

Prophylaxis for malaria

12

Mefloquine (Ariam)

Schizonticide (newest member)
DOC for malarial suppression

13

Narrowest spectrum of activity

Primaquine

14

Most effective against malarial parasite in the liver but not effective within erythrocytes

Primaquine

15

Primaquine

DOC acute attack of Plasmodium

16

Cinchonism manifestations

tinnitus, headache, nausea, disturbed vision

17

Doxycycline

Prophylaxis for malaria

18

Halfantrine

Can arrest tissue conduction in cardiac muscles
Schizonticide

19

Lumefantrine MOA

Inhibition of B- hematinin

20

Most toxic antimalarial drug

Quinacrine

21

Causes the yellow color on the skin

Acridine dye

22

Quinacrine

Tx. for malarial and a SCLEROSING AGENT

23

Semi- synthetic antimalarial agent

Artemissinin

24

CINCHONA ALKALOIDS

Quinine Sulfate
Quinidine

25

4- Aminoquinolines

Mefloquine
Amodiaquine
Chloroquine

26

8-Aminoquinolines

Primaquine

27

Polycyclic Anti-Malarial Drugs

Doxycycline
Halfantrine
Lumefantrine
Quinacrine
Artemisinin