Anti-microbials

Question 1

Bacitracin

Answer 1

Glycopeptides

Inhibits synthesis or damage to cell wall

Question 2

Penicillins

Answer 2

B-lactam

Inhibits synthesis or damage to cell wall

Question 3

Cephalosporins

Answer 3

B-lactam

Inhibits synthesis or damage to cell wall

Question 4

Monobactams

Answer 4

B-lactams - aztreonam

Inhibits synthesis or damage to cell wall

Question 5

Carbapenems

Answer 5

B-lactams - impenem, panipenem, meropenem

Inhibits synthesis or damage to cell wall

Question 6

Polymixins

Answer 6

Inhibits synthesis or damages cytoplasmic membrane

Question 7

Daptomycin

Answer 7

Inhibits synthesis or damage to cytoplasmic membrane

Question 8

B-lactamase inhibitors (name and mechanism)

Answer 8

Clavulanate, sulbactam, tazobactam

Bacterial cell wall inhibitors

Question 9

Tetracyclines

Answer 9

Tetracycline, doxycycline, minocycline

Inhibits bacterial ribosome actions (protein synthesis)

Question 10

Macrolides

Answer 10

Erythromycin, ketolides

Inhibits bacterial ribosome actions (protein synthesis)

Question 11

Aminoglycosides

Answer 11

Streptomycin, gentamicin, neomycin

Inhibits bacterial ribosomal actions (protein synthesis)

Question 12

Spectinomycin

Answer 12

Inhibits ribosomal actions (protein synthesis)

Question 13

Clindamycin

Answer 13

Inhibits bacterial ribosomal action (protein synthesis)

Question 14

Mupirocin

Answer 14

Inhibits bacterial ribosomal actions (protein synthesis)

Question 15

Chloramphenicol

Answer 15

Inhibits ribosomal actions (protein synthesis)

Question 16

Streptogramins

Answer 16

Inhibits ribosomal actions (protein synthesis)

Question 17

Oxazolidinones

Answer 17

Inhibits bacterial ribosomal actions (protein synthesis)

Question 18

Sulfamethoxazole

Answer 18

Sulfonamide

Folate antagonist - inhibits dihydropteroate synthase

Question 19

Sulfadiazine

Answer 19

Sulfonamide

Folate antagonist - inhibits dihydropteroate synthase

Question 20

Sulfamethizole

Answer 20

Sulfonamide

Folate antagonist - inhibits dihydropteroate synthase

Question 21

Sulfasalazine

Answer 21

Sulfonamide

Folate antagonist - inhibits dihydropteroate synthase

Question 22

Sulfisoxazole

Answer 22

Sulfonamide

Folate antagonist - inhibits dihydropteroate synthase

Question 23

Trimethoprim

Answer 23

Bacterial folate antagonist - inhibits dihydrofolate reductase (for THF)

Question 24

Fluoroquinolones

Answer 24

Ciprofloxacin, norfloxacin, levofloxacin, gatifloxacin, moxifloxacin
Inhibits/damages bacterial DNA (modification of synthesis or metabolism of NA)

Question 25

Nitrofurans

Answer 25

Furazolidone, furaltadone, mitrofurantoin, nitrofurazone | Inhibits/damages bacterial DNA (modification of synthesis/metabolism of NA)

Question 26

Colistin (Polymixins E)

Answer 26

Inhibits synthesis/damages to cytoplasmic membranes

Question 27

Polymixin B

Answer 27

Inhibits synthesis/damages cytoplasmic membrane

Question 28

Isoniazid

Answer 28

Anti- TB drug (first line)

Question 29

Rifampin

Answer 29

Anti-TB drug (first line)

Question 30

Rifabutin

Answer 30

Anti-TB drug (first line)

Question 31

Rifapentine

Answer 31

Anti-TB drug (first line)

Question 32

Pyrazinamide

Answer 32

Anti- TB drug (first line)

Question 33

Ethambutol

Answer 33

Anti-TB drug (first line)

Question 34

Vancomycin

Answer 34

glycopeptides | Inhibits synthesis or damage to cell wall