Anti platelet drugs Flashcards
1
Q
What mediators are released when there is injury to a blood vessel wall?
A
ADP
Thromboxane A2
2
Q
What is thromobosis?
A
Pathological formation of a ‘haemostatic’ plug within the vasculature in the absence of bleeding
3
Q
What is the term given to a clot that travels from site where it was formed?
A
Embolism
4
Q
What are the categories in Virchow’s triad?
A
- stasis of blood flow
- endothelial injury
- hyper coagulation
5
Q
What are the three types of anti-platelet drugs?
A
- Cyclo-oxygenase inhibitors
- ADP receptor pathway inhibitors
- Phosphodiesterase inhibitors
6
Q
Why do anti-platelet drugs work better in the arterial circulation ?
A
In faster flowing vessels, the thrombi are mainly composed of platelets and there is less time for an extensive fibrin mesh to form
