Anti-Protozoal Drugs Flashcards
1
Q
Metronidazole (Flagyl)
A
inhibits DNA synthesis, damage DNA
2
Q
Tinidazole
A
Contains a nitro group which is reduced to a free nitro radical
3
Q
Eflornithine (Ornidyl) (hair removal)
A
inhibit ornithine decarboxylase of polyamine biosynthesis
4
Q
Furazolidone (Furoxone)
A
cross-linking DNA
5
Q
Hydroxychloroquine (Plaquenil)
A
block DNA synthesis
6
Q
Iodoquinol (Diquinol, Yodoquinol, Yodoxin)
A
not absorbed, action unknown
7
Q
Pentamidine (Pentam 300)
A
may affect mitochondrial functions
8
Q
Paromomycin
A
inhibits protein synthesis, similar as neomycin
9
Q
Pyrimethamine
A
tetrahydrofolic acid synthesis, block DNA and RNA synthesis
