AntiA Classe III = Inhibiteur VOC K+ Infos Flashcards by Zoé Cardamone

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Q

Mécanisme d’action (AntiA classe III)

A

fav fermeture VOC K+ au nv des tissu conducteurs ❤️
pas d’effet sur dépolarisation + phase plateau
effet sur repolarisation → augmente durée PA
augmente période réfractaire

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Q

Pharmacocinétique (antiA classe III)

A

molécule iodée
1/2 vie très importante ≈ 1 mois
métabolisme → augmentation d’iode dans plasma + urine

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Q

Contre indication (AntiA classe II)

A

-bradycardie
-blocs sino-auriculaires
-blocs auriculo-ventriculaires

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Q

Interactions médicamenteuses (antiA classe III)

A

+ antiarytmiques classe I → TdP
+ ß(-) → bradycardie

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Q

Effets indésirables (antiA classe III)

A

ophtalmiques = dépôt cornéens
hyper/hypothyroïdies
cutanées
pneumopathies essentielle diffuses
troubles hépatiques

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