Antianxiety and substance abuse meds Flashcards

1
Q

how long should a patient be treated for anxiety after stabilization

A

at least 12 months

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2
Q

brand name for alprazolam

A

xanax

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3
Q

brand name for buspirone

A

buspar

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4
Q

brand name for clonazepam

A

klonopin

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5
Q

brand name for diazepam

A

valium

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6
Q

brand name for gabapentin

A

neurontin

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7
Q

brand name for hydoxyzine

A

vistaril

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8
Q

brand name for lorazepam

A

ativan

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9
Q

brand name for propranolol

A

inderal

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10
Q

dosage range for aplrazolam to treat panic disorder

A

start at 1.5mg divided into 3 doses

range 5-6mg daily

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11
Q

FDA approved uses for xanax

A

GAD
panic disorder

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12
Q

off label uses for alprazolam

A

other anxiety disorders
PMDD
acute mania adjunct
acute psychosis adjunct

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13
Q

pregnancy risk with alprazolam

A

avoid

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14
Q

discontinuing antianxiety meds

A

taper all of them to avoid rebound anxiety, withdrawal symptoms, or seizures

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15
Q

contraindications for alprazolam

A

angle-closure glaucoma

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16
Q

starting dosage of buspirone

A

15mg BID at breakfast and lunch

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17
Q

dosage range for buspirone

A

20-60mg qd

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18
Q

FDA approved uses for buspirone

A

anxiety disorders
short term treatment

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19
Q

off label uses for buspirone

A

mixed anxiety/depression
tx resistant depression adjunct

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20
Q

pregnancy risk with buspirone

A

risk v benefit

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21
Q

starting dose for clonazepam

A

0.25mg divided BID

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22
Q

maintenance dosage range for clonazepam

A

0.5-4mg qd divided or at hs

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23
Q

FDA approved uses for clonazepam

A

panic disorder (with or without agorophobia)

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24
Q

off label uses for clonazepam

A

insomnia

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25
Q

labs to monitor for clonazepam

A

CBC
LFT
if seizures or medical illnesses

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26
Q

pregnancy risk for clonazepam

A

avoid

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27
Q

contraindications for clonazepam

A

angle-closure glaucoma
severe liver disease

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28
Q

initial dosage of diazepam

A

2-10mg 2-4x/day

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29
Q

maintenance range for diazepam

A

4-40mg daily in divided doses

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30
Q

FDA approved uses for diazepam

A

anxiety disorders
acute agitation

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31
Q

off label uses for diazepam

A

insomnia
catatonia

32
Q

diazepam dosage adjustment for elderly

A

initial is 2-2.5mg 1-2x/day

33
Q

labs to monitor with diazepam

A

if hx of seizures or medical illnesses
CBC, LFT

34
Q

pregnancy risk for diazepam

A

avoid

35
Q

which antianxiety med has a rectal formulation

A

diazepam

36
Q

contraindication for diazepam

A

angle-closure glaucoma

37
Q

diazepam dosage adjustment for renal/hepatic impairment

A

2-2.5mg

38
Q

dosage range for hydroxyzine

A

50-100mg QID

39
Q

FDA approved uses for hydoxyzine

A

anxiety

40
Q

off label uses for hydroxyzine

A

insomnia

41
Q

geriatric considerations for hydroxyzine

A

avoid in dementia

42
Q

pregnancy risk for hydroxyzine

A

avoid

43
Q

what med cannot be given with hydroxyzine and why

A

citalopram d/t QT prolongation

44
Q

dosage of lorazepam

A

2-3mg in 2-3 divided doses
max 10mg qd

45
Q

FDA approved uses for lorazepam

A

anxiety, anxiety associated with depressive sx

46
Q

off label uses for lorazepam

A

insomnia
alcohol withdrawal
panic disorder
acute mania adjunct
acute psychosis adjunct
catatonia

47
Q

lorazepam dosage adjustment for elderly

A

1-2mg qd in 2-3 divided doses

48
Q

labs to monitor with long term use of lorazepam

A

CBC
LFT
LDH

49
Q

pregnancy risk for lorazepam

A

avoid

50
Q

what is the preferred benzodiazepine for older adults and why

A

lorazepam because of its short half-life

51
Q

which benzodiazepine is preferred for delirium

A

lorazepam

52
Q

contraindications for lorazepam

A

angle-closure glaucoma
sleep apnea

53
Q

lorazepam dosage adjustment for renal/hepatic impairment

A

1-2 mg qd in 2-3 divided doses

54
Q

dosage range for propranolol

A

40-400mg in divided doses

55
Q

off label uses for propranolol

A

akathisia, parkinsonian tremor, PTSD, GAD, violence/aggression

56
Q

pregnancy risk for propranolol

A

risk v benefit

57
Q

contraindications for propranolol

A

bradycardia
bronchial asthma
COPD

58
Q

what are the three substance abuse meds

A

acamprosate
chlordiazepoxide
naltrexone

59
Q

brand name for acamprosate

A

campral

60
Q

brand name for chlordiazepoxide

A

librium

61
Q

brand name for naltrexone

A

revia
vivitrol

62
Q

dosage for acamprosate

A

666mg TID
MUST DOSE TID
no titration required

63
Q

uses for acamprosate

A

maintenance of alcohol abstinence

64
Q

pregnancy risk with acamprosate

A

avoid

65
Q

dosage range for librium

A

15-40mg daily in 3-4 divided doses

66
Q

FDA approved uses for librium

A

anxiety disorders
withdrawal from alcohol

67
Q

pregnancy risk with librium

A

avoid

68
Q

how to dc librium

A

taper by 10mg every 3 days

69
Q

contraindication for librium

A

angle closure glaucoma

70
Q

librium dosage adjustment for renal/hepatic impairment

A

10-20mg qd

71
Q

dosage of naltrexone

A

50mg qd

72
Q

FDA approved uses for naltrexone

A

alcohol dependence
prevention of opioid relapse

73
Q

labs to monitor for naltrexone

A

LFT
UDS for presence of opioids

74
Q

how long does a patient need to be opioid free before starting naltrexone

A

7-10 days

75
Q

contraindications for naltrexone

A

opioid use
acute hepatitis
liver failure

76
Q

rare risk of naltrexone

A

eosinophilic asthma