Flashcards in Antibacterial Agents 4: Inhibitors of DNA Function Deck (15):
In General, DNA inhibiting drugs are (Bactericidal or bacteriostatic)?
Can you name the other classes and their action?
What are the 3 durgs in the Fluoroquinolone class? Yes this IS important to know.
** "most important for exam"
What are each of the 3 Fluoroquinolone effective in treating?
1. Cipro (U)
2. Levo (UR)
3. Moxi (R)
R= Respiratory (gram + cocci)
*Put drugs in alphabetical order and then start with "U" and go all the way to "R"
In general, dugs inhibiting intermediary metabolism are (Bactericidal or bacteriostatic)?
What is the primary mechanism of resistance for Fluoroquinolones?
Alter drug target.
Fluoroquinolones are generally administered via which route?
(Cipro and levo can also be parenteral)
Which bacterias usually cause Respiratory infections?
Which Flouro would you use to treat?
Which bacterias usually cause urinary infections?Which Flouro would you use to treat?
Why doesn't Moxiflocacin treat UTIs?
It doesn't concentrate in urine.
What are the major contraindications and adverse reactions for Fluoroquinolone usage?
1.Children under 12 2. Pregnancy
Due to potential arthopathies.
What is nitrofurantoin primarily used for?
It is a urinary tract antiseptic
Consuming alcohol with this drug leads to nausea, vomiting, cramps, flushing and headache.
Using a sulfonamide in neonate populations can cause
Kernicterus- bilirubin induced brain dysfunction
True or false:
Dihydrofolate Reductase is found only in bacteria.
It is found in humans and bacteria.