Antibacterial Agents Spectrum Flashcards

1
Q

G+ cocci

Streptococcus pneumoniae > pneumonia, otitis media, sinusitis

A
Pen G, Pen V 
Amoxicillin
Vancomycin
Cefepime (4th)
Macrolides 
Clindamycin
Linezolid
Quinupristin / Dalfopristin
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2
Q

G+ cocci

Streptococcus pyogenes > pharyngitis

A

Macrolides

Clindamycin

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3
Q

G+ cocci

“Viridans” Streptococci > endocarditis

A

Vancomycin

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4
Q
G+ cocci
Staphylococcus aureus (MSSA-MRSA) > cutaneous infection, pneumonia, bacteremia, device associated infections
A

MSSA: Oxacillin, Cephalexin (1st), Cefazolin (1st), Clindamycin
MRSA: NO Penicillins, Vancomycin, Clindamycin
Doxycycline (Tetracycline)
Linezolid
Quinupristin / Dalfopristin

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5
Q

G+ cocci

Enterococcus faecium-faecalis > bacteremia, intraabdominal infections, urinary tract infections

A
bacteremia: Pen G, Ampicillin
UTI: Ampicillin
Aminoglycosides
Linezolid
Quinupristin / Dalfopristin
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6
Q

G- cocci

Neisseria gonorrheae > gonorrhea

A

Pen G (though high levels of resistance)

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7
Q

G- rod

E. coli > UTIs, intra-abdominal infections, lower respiratory infections, bacteremias, traveler’s diarrhea

A
Ampicillin, Amoxicillin +/- Clavulanate
Cephalexin (1st)
Cefotaxime (3rd), Ceftriaxone (3rd)
Cefepime (4th)
Carbapenems
Aminoglycosides
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8
Q

G- rod

H. influenza > meningitis, otitis media, sinusitis, community-acquired pneumonia

A
Ampicillin, Amoxicillin +/- Clavulanate
Cefuroxime (2nd), Cefaclor (2nd)
Cefotaxime (3rd)
Azithromycin, Clarithromycin (Macrolides)
Doxycycline (Tetracycline)
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9
Q

G- rod

Klebsiella > urinary tract infections, intra-abdominal infections, lower respiratory infections, bacteremias

A

Ampicillin, Amoxicillin +/- Clavulanate
Cephalexin (1st)
Cefepime (4th)
Aminoglycosides

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10
Q

G- rod

Pseudomonas aeruginosa > nosocomial infections at any site (urinary tract infections, pneumonia)

A
Ampicillin, Amoxicillin +/- Clavulanate
Ceftazidime (3rd)
Cefepime (4th)
Carbapenems
Aminoglycosides
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11
Q

Anaerobes G+ rod

Clostridium difficile > pseudomembranous colitis

A

Vancomycin

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12
Q

Anaerobes G+ rod

Clostridium perfringens-botulinum-tetani

A

Pen G
Carbapenems
Clindamycin

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13
Q

Anaerobes G- rod

Bacteroides fragilis > intraabdominal and brain abscess

A
Piperacillin  -  Tazobactam, 
Ticarcillin - Clavulanate
Cefoxitin (2nd)
Carbapenems
Clindamycin
Chloramphenicol (brain)
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14
Q

Atypical

Chlamydia > trachoma, community-acquired pneumonia, urethitis

A

Azithromycin (Macrolide)

Doxycycline (Tetracycline)

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15
Q

Atypical

Mycoplasma pneumoniae > community-acquired pneumonia

A

Macrolides

Doxycycline (Tetracycline)

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