Antibiotic Action

Question 1

Which antibiotics inhibit nucleic acid synthesis via inhibiting folate synthesis

Answer 1

Trimethoprim
Sulphonamides
Sulphamethoxazole

Question 2

Which antibiotics inhibit nucleic acid synthesis via inhibiting DNA gyrase

Answer 2

Fluroquinolones
Ciprofloxacin

Question 3

Which antibiotic inhibit nucleic acid synthesis via binding to RNA polymerase

Answer 3

Rifampicin

Question 4

Which antibiotic inhibit nucleic acid synthesis via breaking DNA strand

Answer 4

Metronidazole

Question 5

Which antibiotics inhibit cell wall synthesis

Answer 5

Glycopeptides (Vancomycin, Teicoplanin)
Beta lactams
- Penicillin’s (Benzylpenecillin, Amoxicillin, Flucloxacillin)
- Cephalosporin’s (Cephalexin, Cefotaxime, Ceftriaxone)
- Carbapenams (Imipenem, Estapenem)

Question 6

Which antibiotics inhibit protein synthesis

Answer 6

Chloramphenicol
Macrolides
- Clarithromycin
- Erythromycin
Tetracycline’s
- Doxycycline
Aminogylcosides
- Gentamycin
- Streptomycin

Question 7

Which antibiotic is usually used when a patient has penicillin allergy

Answer 7

Macrolides

Question 8

What is used to treat MRSA infections

Answer 8

Aminoglycoside - Vancomycin

Question 9

Antibiotic sensitivity testing

Answer 9

Mueller-hinton agar
Allows standardised diffusion rate of antibiotics away from the disc + throughout the agar
Reliable + Repeatable