antibiotic interactions Flashcards

1
Q

enzyme inhibitors

A

erythromycin, clarithromycin, isoniazid, metronidazole, ciprofloxacin

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2
Q

enzyme inducers

A

rifampicin

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3
Q

absorption

A

absorption of tetracyclines and quinolones reduced by antacids/calcium

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4
Q

Broad-spectrum antimicrobials and oral contraceptives

A

entero-heptic cycling can lead to contraceptive failure

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5
Q

Broad-spectrum antimicrobials and warfarin

A

increased INR

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6
Q

Metronidazole

A

disulfiram-like interaction with alcohol

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7
Q

Aminoglycosides/glycopeptides/colistin with loop diuretics or ciclosporin or tacrolimus

A

nephrotoxicity

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8
Q

quinolones and steroids

A

tendonitis

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9
Q

quinolones and NSAIDs

A

convulsions

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10
Q

Macrolides/quinolones

A

Q-T prolonging drugs

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