antibiotic resistance Flashcards

1
Q

state 3 ways the antibodies kill bacteria

A
  • prevent wall synthesis
  • disrupt cell membranes
  • interfere with protein synthesis
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2
Q

describe how antibodies prevent wall synthesis

A
  • inhibit enzymes making cell wall molecules
  • bacteria dies from leakage or lyse from water entry
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3
Q

describe how antibodies disrupt cell membranes

A
  • bind to phospholipids
  • distort structure
  • makes them too permeable
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4
Q

describe how antibodies interfere with protein synthesis

A
  • attach onto bacterial ribosomes
  • prevents protein synthesis
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5
Q

how does antibiotic resistance occur?

A
  • random mutation in bacteria population
  • provides a selective advantage
  • antibiotics only kill non resistant bacteria
  • resistant bacteria can grow and reproduce with no competition, passing on the allele
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6
Q

where is the mutated gene for resistance found?

A

in plasmid DNA

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7
Q

what is causing antibiotic resistance?

A
  • widespread use
  • misuse
  • strengthens selective pressure
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8
Q

why is antibiotic resistance a problem?

A
  • we are less able to treat potentially life threatening bacterial infections
  • can’t easily get rid of bacteria without antibiotics
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9
Q

state 2 ways we can overcome antibiotic resistance

A
  • developing new antibiotics
  • modifying existing ones
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10
Q

give an example of antibiotic resistant bacteria

A

MRSA
- causes serious wound infections
- resistant to several antibiotics including meticillin

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11
Q

how can the likelihood of antibiotic resistance developing be reduced?

A
  • doctors are encouraged to reduce use of antibiotics
  • not to prescribe for minor infections
  • patients are advised to finish the whole course
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12
Q

state 2 risks of using antibiotics

A
  • side effects
  • allergic reactions
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