Antibiotics

Question 1

Aerobic

Answer 1

need oxygen to survive

Question 2

anaerobic

Answer 2

do not need oxygen

Question 3

anti bacterial

Answer 3

active against bacteria

Question 4

bacterial resistant

Answer 4

ability to produce substances that inactivate or destroy the impact of a drug

Question 5

bacteriostatic

Answer 5

Drugs that slow or retard the multiplication of bacteria

Question 6

cross sensitive

Answer 6

allergy to drugs in the same or related group

Question 7

Broad spectrum

Answer 7

drugs effective of gram negative and gram positive bacteria

Question 8

normal flora

Answer 8

non pathogenic microorganism within or on the body

Question 9

super infection

Answer 9

an overgrowth of bacteria or fungal microorganism not affected by the antibiotic being used for treatment

Question 10

The effectiveness of individual antibiotics depend on these 3 factors

Answer 10

The location of the infection

ability of the antibiotic to reach the site of infection

ability of the bacteria to resist or inactivate the drug

Question 11

Sulfonamides Action

Answer 11

Slows the multiplication enough that bodys immune system is able to rid the bacteria

Question 12

Sulfonamides

Adverse reactions

Answer 12

Decrease in WBC, Platelets and RBC

Photosensitivity(easy burned)

Anorexia

Stephens Johnsons syndrome

Question 13

Sulfonamides should be used cautiously for g6pd pts because it can cause what condition?

Answer 13

Hemolysis ( Dose Related)

Question 14

using Sulfonamides you should consider what other allergy?

Answer 14

Sulphur allergies

Question 15

Examples of other drugs containing sulfonamide chemical group?

Answer 15

Celecoxib
Glyburide
Furosemide
Acetazolamide

Question 16

Sulfonamides Contraindications

Answer 16

Do not use near end of pregnancy( can cause significant blood levels)

Use with caution with asthma patients

Question 17

Sulfonamides example

Answer 17

Trimethoprim/Sulfamethoxazole(bactrim)

Silver sulfadiazine (Silvadene TOPICAL)

Question 18

Sulfonamides uses

Answer 18

urinary track infections, MRSA and burns

Question 19

Penicillins Actions

Answer 19

Prevents bacteria from using a substance that is necessary for the maintenance of the bacteria’s outer wall

Question 20

Penicillins use

Answer 20

UTI
Gonorrhea 
Pneumonia 
otitis media 
sinusitis 
strep
tonsillitis 
meningitis 
abdominal infections

Question 21

Penicillins Contraindications

Answer 21

Hypersensitivity to PCN and Cephalosporin meds

Question 22

Penicillins adverse reactions

Answer 22

Mild nausea, vomiting, diarrhea, sore tongue, or mouth

Question 23

PNC Ecamples

Answer 23

Pen VK
Amoxicillin
Amoxicillin/clavulanate (augmentin)

Question 24

Cephalosporines Action

Answer 24

Affect the bacterial cell wall (similar to PNC)

Question 25

Cephalosporines USE

Answer 25

``` infections caused by Strep, staph, Citrobacter, gonocci, Chigella, Clostridia ```

Question 26

Cephalospines adverse reactions

Answer 26

GI disturbances like nvd

Question 27

Cephalosporines contraindication

Answer 27

allergy to cephalosporin or PNC

Question 28

Cephalosprines 1st gen examples

Answer 28

Cephalexin(keflex) | Cefazolin(ancef)

Question 29

Cephalosprines 2nd gen examples

Answer 29

Cefaclor Cefprozil Cefoxitin

Question 30

Cephalosprines 3rd gen example

Answer 30

Ceftriaxone (Rocephrin)

Question 31

Tetracyclines action

Answer 31

Inhibit bacterial protein synthesis necessary for reproduction

Question 32

Tetracycline uses

Answer 32

Treatment of rickettsia(RMSF, Typhus and Tick Fever) Skin and soft tissue infections when PCN is contraindicated

Question 33

Tetracycline adverse reactions

Answer 33

Upset Gastrointestinal tracks, Photosensitivity Can cause permanent discoloration to the teeth for children under 9.

Question 34

Tetracycline contraindication

Answer 34

Pregnancy class D

Question 35

Tetracycline Example

Answer 35

Doxycycline

Question 36

Macrolides Action

Answer 36

Bind to cell membrane and causes changes in protein synthesis

Question 37

Macrolides uses

Answer 37

Community acquired pneumonia H Pylori Alternative to PCN for strep throat

Question 38

What do you combine to treat H Pylori

Answer 38

Clarithromycin with amoxicillin and a PPI

Question 39

Macrolides adverse reactions

Answer 39

GI upset

Question 40

Macrolides contraindication

Answer 40

Liver disease

Question 41

Macrolides example

Answer 41

Azithromycin (ZPAK) Erythromcin (Eye ointment) Clarithromycin

Question 42

Fluoroquinolones Action

Answer 42

interfere with an enzyme needed by bacteria for synthesis of dna. Prevents cell reproduction leading to death.

Question 43

Fluoroquinolones USE

Answer 43

LRI Atypical pneumonia std uti

Question 44

Fluoroquinolones Adverse reactions

Answer 44

Super infections Pain inflamation and rupture of tendona Photosensitive Colitis

Question 45

Fluoroquinolones Contraindications

Answer 45

Children younger than 18 Pregnancy cat C History of seizures

Question 46

Fluoroquinolones Examples

Answer 46

Ciprfloxacin : Cipro | Levofloxacin: Levaquin

Question 47

na

Answer 47

na

Question 48

Aminoglycosides use

Answer 48

Primary gram negative | GI Infections

Question 49

Aminoglycosides Adverse reactions

Answer 49

nephrotocicity ototoxicity neurotoxicity

Question 50

Aminoglycosides Contraindications

Answer 50

Long term therapy pre existing hearing loss During lactation Pregnancy Cat D

Question 51

Aminoglycosides Examples

Answer 51

Gentamicin | Neomycin

Question 52

Carbapenems Action

Answer 52

Inhibits cell wall synthsis by binding to penicillin binding proteins which inhibit final step in cell wall synthesis

Question 53

Aminoglycosides Use

Answer 53

Severe drug resistan infections Hospital acquired pneumonia , Prosthetic joint infections, necrotizing soft tissue infection and pyelonephritis

Question 54

Aminoglycosides adverse reactions

Answer 54

Seizuere, renal failure or C diff

Question 55

Aminoglycosides Contraindications

Answer 55

Seizure disorder Stevens- Johnsons disorder Renal Impairment

Question 56

Aminoglycosides Examples

Answer 56

Ertapenem

Question 57

Lincosamide action

Answer 57

Decrease adherence of bacteria to host cell by disrupting protein synthesis and changing cell wall surface

Question 58

Lincomycin Example

Answer 58

Clindamycin

Question 59

Amebacide, Antiprotozoal, Nitoimidazole Example

Answer 59

Metronidazole