Antibiotics Flashcards

(51 cards)

1
Q

Define stewardship

A
  • identifying the small group of people that require antibiotics
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What are the 4 c’s to avoid

A
  • co-amoxiclav
  • cephalosporins (ceftriaxone)
  • clindamycin (macrolide)
  • ciprofloxacin (fluoroquinolone)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Why are the 4 c’s avoided

A
  • increased c . diff risk
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Name a cephalsporin

A
  • ceftriaxone
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Where are anaerobic organisms found?

A
  • mouth
  • teeth
  • throat
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Where are gram negative bacteria found?

A
  • Gastrointestinal
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

General antibiotic side effects

A
  • nausea
  • vomiting
  • diarrhoea
  • rashes
  • candida
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Flucoxacillin and co-amoxacillin side effect

A
  • cholestatic jaundice
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Vancomycin side effect

A
  • red man syndrome
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Tetracycline side effect

A
  • photosensitivity
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What may affect tetracycline and quinolone absorption?

A
  • calcium
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Broad spectrum antibiotics given to a patient on warfarin may cause?

A
  • increased INR
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What must be avoided when on metrondiazole

A
  • alcohol
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What drugs a B lactams found in?

A
  • penicillin
  • cephaloporins
  • carbapenems
  • aztreonam
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Commonest CNS infection bug?

A
  • s. pneumonia

- ceftriazone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Commonest lung infection bug and treatment

A
  • s.pneumonia (amoxicillin, doxycycline)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

H.influenzae lung infection treatment

A
  • co - amoxiclav

- amoxicillin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

1st line for a c.diff gut infection?

A
  • oral vancomycin
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

What does the gram negatives have on their cell wall that gram positive don’t?

A
  • lipopolysaccharide

- can cause shock

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Name a gram negative cocci

A
  • neisseria
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Gram neg bacilli examples

A
  • pseudomonas
  • e.coli
  • klebsiella
  • salmonella
22
Q

What are coliform

A
  • always present in gi tract

- e.coli and similar

23
Q

What is atypical bacteria?

A
  • less common bugs

- not strep

24
Q

Hospitalised patients more susceptible to ____ bacteria

A
  • gram negative
25
Chronic lung disease now infection, what bugs?
- pseudomonas (CF patient) - pneumococcus - influenza
26
What bug peaks every 4 years
- mycoplasma
27
Bug associated with lamb season and sheep farming
- coxiella
28
Treatment for haemophilus influenzae?
- amoxicillin
29
H. influenzae is what category of bug?
- gram negative coccobacilli
30
How are atypical pneumonias treated?
- not strep - treated with doxycycline - legionella = quinolones, clarithromycin
31
How is legionella treated?
- quinolones | - clarithromycin
32
What antibiotic coverage is lost in ESBLs
- penicillin - cephalosporins - aztreonam
33
What must be monitored when giving gentamicin?
- renal function
34
Corynebacterium is seen in what condition and what is it categoriesed as?
- seen in diptheria | - gram positive bacilli
35
Name some gram positive bacilli?
- corynebacterium - clostridium - listeria - bacillus
36
Alpha haemolytic means?
- partial haemolysis - green - pneumonia - viridian's
37
Beta haemolytic means
- complete haemolysis - s.pyogens - group b strep (agalctiae)
38
Group B strep example. and when is it seen?
- s. agalactiae - pregnancy - neonate
39
Treatment of enterococci?
- iv amoxicilllin | - vancomycin
40
What route should antibiotics be given in sepsis?
- IV | - except for sepsis due to c.diff in which oral vancomycin is given
41
Treatment for a staphylococci infection?
- flucoxacillin
42
What infections are gram positive bacilli seen?
- intra abdo infection - skin and soft tissue - prosthetic material - meningitis/encephalitis - PWID
43
What is the typical organism in Pneumonia?
- s. pneumonia
44
Name some atypical pneumonia bugs?
- mycoplasma - legionella - chamydophila - psittaci
45
Immunosuppressed patients are more susceptible to what pneumonias
- jiroveci - aspergillus - TB
46
What do vaccines aim to target for s.pneumonia?
- the virulence factors
47
Cystic fibrosis patient with pneumonia?
- pseudomonas aeruginosa
48
What is the difficulty at diagnosing fungal infections?
- hard to culture and sample
49
How is aspergillosis diagnosed?
- broncho-alveolar lavage - galactomman as a marker - septate hyhae on microscope
50
Commonest strain of aspergillosis?
- fumigatus
51
Who is most susceptible to an aspergillosis infection?
- immunocompromised - transplant patients - chemotherapy