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PHARMACOLOGY > Antibiotics > Flashcards

Antibiotics Flashcards

(45 cards)

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1
Q

Name 3 antibiotics that target DNA replication

A

Ciprofloxacin
Levofloxacin
Metronidazole

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2
Q

Name 2 antibiotics that target folate synthesis

A

Trimethoprim

Methotrexate

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3
Q

Name 3 antibiotics that target protein synthesis

A 
Tetracycline
Doxycycline 
Chloramphenicol
Gentamycin
Erythromycin
Clarithromycin
Clindamycin
Linezolid
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4
Q

Name 3 antibiotics that target cell wall synthesis

A 
ceftriaxone
carbapenems
penicillin V
amoxicillin
flucloxacillin
vancomycin
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5
Q

Name 3 antibiotics that target RNA synthesis

A

Rifampicin
Ethambutol
Isoniazid
Pyrazinamide

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6
Q

Tetracyclines

A

doxycycline, tetracycline

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7
Q

Macrolides

A

erythromycin
azithromycin
clarithromycin

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8
Q

Aminoglycosides

A

gentamycin
tobramycin
streptomycin

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9
Q

Cephalosporins

A

cefuroxime
ceftriaxone
cefacalor

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10
Q

Fluroquinolones

A

ciprofloxacin
levofloxacin
gemifloxacin

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11
Q

Rifampicin side effects

A

orange pee and sweat

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12
Q

Isoniazid side effects

A

hepatitis and neuropathy

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13
Q

Pyrazinamide side effects

A

hepatitis and joint pain

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14
Q

Ethambutol side effects

A

blindness

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15
Q

Metronidazole covers…

A

anaerobes

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16
Q

Gentamicin covers…

A

gram negatives

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17
Q

UTI Abx

A

Nitrofurantoin or trimethoprim for 3/7 days

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18
Q

Tonsillitis Abx

A

FeverPAIN >3

penicillin / clarithromycin 5 days

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19
Q

CAP Pneumonia Abx

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A

mild / mod - penicillin / doxycycline (5days)

severe - co-amoxiclav + doxycycline

20
Q

HAP Pneumonia Abx

Study These Flashcards
A

Mild / Moderate - Penicillin / doxycycline (5 days)

Severe - IV amoxicillin + gentamicin

21
Q

Penicillin allergic sepsis of unknown origin Abx

Study These Flashcards
A

IV vancomycin, metronidazole and gentamycin

22
Q

Meningitis Abx

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A

ceftriaxone and IV dexamethasone
+ acyclovir if encephalitis suspected
+ amoxicillin if immunocomprimised or <3mths / >60yrs (listeria cover)

23
Q

subacute native valve endocarditis Abx

Study These Flashcards
A

amoxicillin + gentamycin

24
Q

acute native valve endocarditis Abx

Study These Flashcards
A

flucloxacillin

25
prosthetic valve / suspected MRSA endocarditis Abx
vancomycin + gentamicin
26
Cellulitis Abx
flucloxacillin / doxycycline 5-7 days
27
open fracture prophylaxis Abx
Cefuroxime 1.5g every 8 hrs max 3 days (start within 3 hrs)
28
Acute septic arthritis or osteomyelitis
IV flucloxacillin
29
Diabetic foot infection
mild - PO flucloxacillin (7days) | mod - flucloxacillin + metronidazole (7days)
30
C.Diff Infection
non-severe - metronidazole (10 days) | severe - vancomycin +/- metronidazole (10 days)
31
Recurrent C.Diff infection within 12 wks of positive stool test
Fidaxomicin 10 days
32
Acute COPD exacerbation Abx
1. amoxicillin 500mg tds | 2. doxycycline
33
Pyelonephritis Abx
co-trimoxazole or co-amoxiclav
34
Uncomplicated chlamydia
doxycycline 100mg bd (7days) or azithromycin (3days)
35
Mastitis
If symptoms don't improve after 12-24 hrs then use flucloxacillin or clindamycin
36
Breast Abscess
Flucloxacillin or clindamycin (7-10 days) + drainage
37
Orbital Cellulitis
IV flucloxacillin, ceftrixone +/- metronidazole | step down = oral co-amoxiclav
38
Glandular fever Abx
NONE - if started stop any antibiotics unless underlying secondary infection
39
Bacterial conjunctivitis Abx
topical chloramphenicol
40
Endophthalmitis
intravitreal vancomycin + ceftazidime
41
Antibiotics that cause C.Diff
Clindamycin Clarithromycin Co-amoxiclav Ciprofloxacin
42
doxycycline and tetracycline side effects
hepatoxicity, teeth staining, photosensitivity, dysphagia
43
macrolides - azithromycin, clarithromycin and erythromycin side effects
GI disturbance, hepatitis and prolonged QT
44
Enzyme dependent drugs such as ... may have reduced clearance by antipsychotics such as carbamazepine
- Erythromycin - Clarithromycin - Isoniazid - Metronidazole - Ciprofloxacin
45
Broad spectrum abx can cause...
- failure of oral contraceptives | - increased INR in warfarin patients

PHARMACOLOGY (2 decks)

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