Antibiotics Flashcards

1
Q

Penicillin spectrum

A

Gram +ve and anaerobes

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2
Q

Mode of action of penicillin

A

Inhibits cell wall synthesis, bactericidal

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3
Q

Licenced routes of penicillin

A

IM
Lactating cow
Oral

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4
Q

Amoxicillin spectrum

A

Broad spectrum
Better gram -ve than +ve

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5
Q

Amoxicillin mode of action

A

Inhibits cell wall synthesis, bactericidal

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6
Q

Licensed routes of amoxicillin

A

IM
Dry cow preparations
Oral

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7
Q

Tetracyline spectrum

A

Broad spectrum, gram +ve and -ve, some anaerobes
Active against Mycoplasma and Chlamydia

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8
Q

Which licensed farm animal antibiotics are active against Mycoplasma?

A

Tetracyclines and aminoglycosides

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9
Q

Which licenced farm animal antibiotic is effective against Chlamydia?

A

Tetracyclines

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9
Q

Action of tetracyclines

A

Inhibits protein synthesis, bacteriostatic

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10
Q

Licensed routes of tetracylines

A

IV
IM
Oral
Intra-uterina
Aerosol spray

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11
Q

Antibiotics that can be delivered IV (important if cow is sick)

A

Tetracylines
Trimethoprim sulphonamides

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12
Q

Spectrum of trimethoprim sulphonamides

A

Broad spectrum, some anaerobes

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13
Q

Mode of action of trimethoprim sulphonamides

A

Inhibits folate pathway of bacteria, bacteriostatic

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14
Q

Licensed routes of trimethoprim sulphonamides

A

IV
IM
Subcutaneous
Oral

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15
Q

Aminoglycoside/spectinomycin spectrum

A

Broad spectrum, gram +ve and some gram -ve
Little anaerobic activity
Mycoplasma

16
Q

Aminoglycoside/spectinomycin mode of action

A

Inhibits protein synthesis, bactericidal

17
Q

Licensed route of aminoglycoside/spectinomycin in farm animals

A

Oral

18
Q

Which farm animal antibiotics can penetrate abscesses?

A

Penicillins
Amoxicillin

19
Q

Which farm animal antibiotics can penetrate soft tissues?

A

Penicillins
Amoxicillin

20
Q

Where do tetracyclines have a good distribution?

A

Urinary tract, respiratory tract and intestines

21
Q

What can inactivate trimethoprim sulphonamides?

A

Pus/necrotic tissue

22
Q

Antibiotics with good distribution in GIT

A

Trimethropin sulphonamides
Aminoglycosides/spectinomycin (stays in GIT after oral administration)