Antibiotics

Question 1

Zyvox

Answer 1

(linezolid); IV or PO; gram + coverage only (good MRSA)

SE: thrombocytopenia

Question 2

Vancomycin

Answer 2

covers staph (MRSA); SE: red man syndrome, oto/nephrotoxic

Question 3

Zosyn

Answer 3

(piperacillin & tazobactam); covers pseudomonas; renally excreted

Question 4

Levaquin

Answer 4

good for pneumonia; E.coli resistance; DNA gyrase inhibitor; renally cleared

Question 5

Flagyl

Answer 5

(metronidazole); good gram - coverage, anerobic coverage

Question 6

Imipenem

Answer 6

(primaxin)

Question 7

Rocephin

Answer 7

(ceftriaxone)

Question 8

Avelox

Answer 8

(moxifloxacin); AECB; acute bacterial sinusitis; CAP; covers staph, strep pneumoniae, H influenzae, enterobacter

Question 9

3 antibiotics to use for lungs:

Answer 9

Zithromax
Doxy (100 mg BID x7d)
Bactrim DS (160 mg BID)

Question 10

Treatment for CAP, general

Answer 10

quinolone monotherapy OR rocephin/zithromax

Question 11

If CAP patient is immunocompromised, what 2 organisms do you need to cover?

Answer 11

MRSA, pseudomonas (vanco & zyvox)

Question 12

Daptomycin

Answer 12

covers MRSA, but not effective for lung treatment; doesn’t cross surfactant

Question 13

Tigecycline (Tygacil)

Answer 13

MRSA coverage; binds to 30s subunit; static; works well below the diaphragm;
Gram +/-, anerobic, MRSA coverage
NO PSEUDOMONAS coverage
good for pericarditis, diverticulitis

Question 14

Treatment for Strep Pneumonia

Answer 14

PCN (20-25% resistance)…may need Vancomycin too

Question 15

Healthcare Associate Pneumonia treatment

Answer 15

Vancomycin & Zosyn

Question 16

Ciprofloxacin

Answer 16

does not have good lung penetration

Question 17

T/F Cephalosporins cover pseudomonas

Answer 17

True

Question 18

Clindamycin

Answer 18

anerobic coverage above the diaphragm; gram + , oral

Question 19

Treatment options for C Diff?

Answer 19

Oral Vancomycin
Oral/IV Flagyl
Dificid (fidaxomicin) - 200 mg po BID x10d

Question 20

Diflicid

Answer 20

(fidaxomicin); bacteriocidal, inhibits RNA synthesis; macrolide abx.

Question 21

Pseudomonas coverage:

Answer 21

Aminoglycosides
Zosyn
Ceftazasone
Imipenem
Cipro PO

Question 22

Ceftin

Answer 22

good for CAP to send home; 2nd generation floroquinolone, covers E. Coli; NO atypical coverage

Question 23

Augmentin

Answer 23

good for E. coli; sinusitis

Question 24

Name IV antibiotics

Answer 24

Zithromax
Zyvox
Zosyn
Unasyn
Vancomycin
Ceftazazone
Rocephin
Gentamycin
Teflaro

Question 25

Name 3 abx with Atypical coverage

Answer 25

Levaquin Avelox Zithromax