Antibiotics

Question 1

These 3 ABX are metabolized by the liver

Answer 1

Ceftriaxone
Macrolides (azithromycin)
Metronidazole

Question 2

Two ABX that my raise INR?

Answer 2

Metronidazole

TMP-SMX

Question 3

ABX that can decrease INR?

Answer 3

Rifampin

Question 4

ABX that cause dysrhythmia?

Answer 4

Macrolides
Fluroquinolones (not recommended with other drugs that prolong QT)

Question 5

ABX associated with Ototoxicity?

Answer 5

Aminoglycosides (gentamicin)

Minocycline

Question 6

ABX associated with Nephrotoxicity?

Answer 6

Amphotericin B (amphoterrible)
Aminoglycosides (cause ATN, i.e. gentamicin)
Vancomycin

Question 7

ABX that causes DISULFURAM reaction?

Answer 7

Metronidazole

Question 8

ABX that causes “Red Man Syndrome”?

Answer 8

Vancomycin –> slow the infusion

Question 9

ABX that turns bodily fluids red?

Answer 9

Rifampin

Question 10

ABX that causes discolored teeth?

Answer 10

Tetracyclines (not used in children <8)

Question 11

ABX that causes yellow babies? Why?

Answer 11

Sulfonamides - turn yellow from displaced bilirubin

Question 12

ABX with highest prevalence of C.diff?

Answer 12

aminopenicillins, cephalosporins, fluroquinolones

Question 13

ABX with highest incidence of C.diff?

Answer 13

Clindamycin

Question 14

ABX contraindicated in pregnancy?

Answer 14

Aminoglycosides, Tetracyclines

Question 15

Aminoglycosides in pregnancy cause?

Answer 15

Possible CN 8 toxicity in fetus

Question 16

Tetracyclines in pregnancy cause?

Answer 16

Teeth/bone problems in infant

Question 17

Sulfonamides in pregnancy cause?

Answer 17

Newborn kernicterus

Question 18

Fluroquinolones in pregnancy cause?

Answer 18

Athropathy

Question 19

PO Anti-MSSA ABX?

Answer 19

dicloxacillin, cephalexin

Question 20

PO Anti-MRSA ABX?

Answer 20

Linezolid, Doxycycline, TMP-SMX

Question 21

PO Anti-pseudomonal ANX?

Answer 21

Ciprofloxacin, levofloxacin

Question 22

PO Anti-VRE ABX?

Answer 22

Linezolid

Question 23

IV Anti-MSSA ABX?

Answer 23

nafcillin, cefazolin, vancomycin

Question 24

IV Anti-MRSA ABX?

Answer 24

Vancomycin

Question 25

IV Anti-Pseudomonal ABX (Aspiration)?

Answer 25

Piperacillin/tazobactam

Question 26

IV Anti-VRE ABX?

Answer 26

Linezolid, Daptomycin