Antibiotics

Question 1

What targets DNA gyrase-ATP complex?

Answer 1

quinolones/floroquinones

Question 2

What targets DNA gyrase?

Answer 2

novobiocin and ciprofloxacin

Question 3

What targets DNA dependent RNA polymerase

Answer 3

Rifampin

Question 4

What targets PBPs and prevents cross linking?

Answer 4

B-lactams (penicillin, cephalosporin, carbapenems, monobactams)

Question 5

What targets PBPs and prevents transglycosylation?

Answer 5

Vancomycin

Question 6

What prevents recycling of undecaprenyl-P-P carrier?

Answer 6

Bacitracin

Question 7

What prevents the attachment of the pentrapeptide chain?

Answer 7

Cycloserine

Question 8

What prevents NAM synthesis from NAG?

Answer 8

Fosfomycin

Question 9

What is a competitive inhibitor of dihyrofolate reductase?

Answer 9

Trimethoprim

Question 10

What is a competitive inhibitor of dihydropteroic acid synthase?

Answer 10

Sulfonamides

Question 11

What disrupts the cell membrane?

Answer 11

Polymixins

Question 12

What targets the 30S subunit and prevents oxidative transport (initiation)?

Answer 12

aminoglycosides

Question 13

What targets the 30S subunit and prevents initiation of translation?

Answer 13

oxazolidinones

Question 14

What targets the 30S subunit and prevents loading acceptor site?

Answer 14

Tetracyclines

Question 15

What targets the 50S and prevents peptide bond formation?

Answer 15

Lincosamides and Chloramphenicol

Question 16

What targets the 50S and causes release of the peptide chain?

Answer 16

Macrolides

Question 17

What targets the 50S and blocks the P site?

Answer 17

Streptogramins

Question 18

Which antibiotics targets steps in cell wall synthesis?

Answer 18

Fosfomycin and cycloserine

Question 19

What antibiotic targets cell membrane step?

Answer 19

Bacitracin

Question 20

What antibiotics target cell wall steps?

Answer 20

Vancomycin and B-lactams

Question 21

What antibiotics target folic acid synthesis?

Answer 21

Sulfonamides and Trimethoprim

Question 22

What antibiotic targets cell membrane?

Answer 22

Polymyxin

Question 23

What antibiotics targets DNA replication?

Answer 23

Floroquinolones/quinolones, novobiocin, ciprofloxacin

Question 24

What antibiotic target transcription?

Answer 24

Rifampin

Question 25

What antibiotics target protein synthesis (specifically the 30 S subunit)?

Answer 25

Aminoglycosides, oxazolidinones, and tetracylines

Question 26

What antibiotics target protein synthesis (specifically the 50 S subunit)?

Answer 26

Cholaremphenicol, macrolides, and streptogramins?