Antibiotics Flashcards

(75 cards)

1
Q

bacteriostatic

A

inhibits a metabolic pathway

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

bactericidal

A

outright kills bacteria via lysis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

sulfonamide mechanism

A

inhibits dihydropteroate synthesis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

sulfonamide contraindication

A

pregnancy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

sulfonamide synergizes with

A

DHFR inhibitor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

sulfisoxazole w/erythromycin

A

oral SULF for otitis media

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

sulfamethoxazole w/trimethoprim

A

oral SULF for urinary, respiratory, and GI infections

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

dapsone

A

oral SULF for leprosy and pneumonia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

sulfacetamide

A

topical SULF for ulcerative blepharitis and bacterial conjunctivitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

silver sulfadiazine

A

topical SULF for burns and preventing sepsis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

mafenide

A

topical SULF for burns

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

crystalluria

A

crystals in urine (SULF SE)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

kernicterus

A

bilirubin encepalopathy (SULF SE)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

blood discrasias

A

SULF SE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

hypersensitivity

A

SULF SE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

erythema multiforme

A

asymptomatic macules on extremities

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Stevens-Johnson Syndrome

A

blisters in airway/mouth

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Rx fever

A

hypersensitivity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

hyperkalemia

A

high potassium

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

fluoroquinolone mechanism (G-)

A

inhibits DNA gyrase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

fluoroquinolone mechanism (G+)

A

inhibits topoisomerase IV

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

cirpofloxacin

A

2nd gen FQ for anthrax [decreases theophylline clearance, inhibits CYP3A4/CYP1A2]

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

ofloxacin

A

2nd gen FQ [avoid if bacterial resistance or liver disease]

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

gatifloxacin

A

3rd gen FQ [avoid if pt has diabetes]

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
gemifloxacin
3rd gen FQ for chronic bronchitis and pneumonia
26
levofloxacin
3rd gen FQ [avoid if cardiac conduction anomalies]
27
motifloxacin
3rd gen FQ [avoid if hepatic disease]
28
besifloxacin
4th gen FQ for bacterial conjunctivitis
29
finafloxacin
4th gen FQ for otitis externa
30
phototoxicity
burning, redness, swelling, blisters, rash (FQ SE)
31
arthropathy
damages growing cartilage (FQ SE)
32
peripheral neuropathy
FQ SE
33
tendon rupture
FQ SE & black box warning
34
diplopia
tendonitis of extraocular muslces (FQ SE)
35
C difficile
induces diarrhea and pseudomembranous colitis
36
fidaxomicin
FQ for C difficile
37
penicillin mechanism
inhibits transpeptidase
38
penicillinases
beta-lactamases
39
Pfizerpen
IM/IV PCN G
40
procaine
local anesthetic that slows absorption of PCN
41
benzathine
long-acting suspension for PCN
42
penicillin V
oral [food interferes]
43
dicloxacillin
PCNase resistant oral PCN
44
oxacillin
PCNase resistant parenteral PCN
45
nafcillin
PCNase resistant parenteral PCN
46
ampicillin
oral or IV aminoPCN
47
sulfactam
PCNase inhibitor given with ampicillin
48
unasyn
given with ampicillin due to bacteroides fragilis
49
amoxicillin
tables, oral suspension, or pediatric drop aminoPNC for otitis med or prophylaxis
50
augmentin
amoxicillin + clavulanate
51
clavulanate
beta-lactamase inhibitor given with amoxicillin
52
ticarcillin + clauvulanate
parenteral
53
piperacillin + tazobactam
parenteral
54
tazobactam
beta-lactamase inhibitor given with piperacillin
55
superinfection
kill off organisms that allow others to grow w/o competition
56
Jarish-Herxheimer reaction
found in patients with secondary syphilis
57
cephalosporin mechanism
inhibit transpeptidase
58
cephalosporin advtantage
resistant to many PCNases
59
cefazolin
1st gen IV CF for G+ and PEcK G-
60
cephalexin
1st gen oral CF for G+ PEcK G-
61
cefadroxil
1st gen oral CF for G+ and PEcK G-
62
cefaclor
2nd gen oral CF for HNPEcK
63
cefuroxime
2nd gen oral/IV/IM CF for HNPEcK
64
cefoxitin
2nd gen IV/IM CF for bacteriodes fragilis
65
cefotetan
2nd gen IV/IM CF [antagonizes vitamin K, must be supplemented]
66
cefprozil
2nd gen oral CF
67
ceftriaxone
3rd gen IV CFF [flush line between doses]
68
cefotaxime
3rd gen IV/IM CF
69
ceftazidime
3rd gen IV/IM CF [dont use if history of epilepsy]
70
cefpodoxime
3rd gen oral CF
71
cefdinir
3rd gen oral CF [decreases absorption]
72
cefepime
4th gen IV/IM CF [don't use if hx of epilepsy)
73
cefditoren
4th gen prodrug CF activated via esterase hydrolysis
74
cefaroline
advanced gen IV prodrug CF for community bacterial pneumonia and MRSA
75
cefolozane
advanced gen CF for complicated UTIs and kidney infection