Antibiotics

Question 1

B-lactam drugs, bacitracin, vancomycin

Answer 1

antibiotics that target cell wall synthesis

Question 2

B-lactam drugs

Answer 2

bind and inactivate transpeptidases

Question 3

penicillin G and V

Answer 3

penicillin that works only against gram positives

Question 4

methicillin and dicloxicillin

Answer 4

penicillinase resistant antibiotics

Question 5

ampicillin and amoxicillin

Answer 5

broad spectrum penicillins

Question 6

ticarcillin and piperacillin

Answer 6

extended spectrum penicillins - more effective against gram negatives, but can still be inactivated by beta-lactamases

Question 7

augmentin

Answer 7

penicillin + beta-lactamase inhibitor (amoxicillin and clavulanic acid)

Question 8

cephalosporin

Answer 8

B-lactam drug - has 4 generations. broader spectrum against gram negative, each generation is more resistant to beta-lactamases

Question 9

carbapenems

Answer 9

B-lactam drug works against cell wall synthesis - very resistant to eta-lactamases. broad spectrum

Question 10

monobactams

Answer 10

B-lactam drug works against cell wall synthesis of gram negative enterbacteria

Question 11

bacitracin

Answer 11

drug that works on cell wall synthesis - acts on the bactoprenol that transports peptidoglycan monomers out of the cell

Question 12

vancomycin

Answer 12

drug that works on cell wall synthesis - binds to the tretrapeptide side chain, not penicillin binding proteins

Question 13

aminoglycosides

Answer 13

changes shape of ribosome blocking initiation and caises misreading of mRNA

Question 14

streptomycin, gentamicin, neomycin

Answer 14

aminoglycosides, drugs that bind to the ribosome

Question 15

tetracycline/doxycycline

Answer 15

block attachment of tRNAs reversibly

cause discoloration of teeth

Question 16

glycylcycline

Answer 16

wider spectrum than tetracycline - blocks attachment of tRNA

Question 17

macrolide

Answer 17

prevents continuation of protein synthesis

works on Gram positive, not negative