antibiotics Flashcards
(22 cards)
Excreted by urine unchanged; mostly t1/2=30-90mins
B-lactams
poor cns and prostate penetration
B-lactams
DOC for group A strep; meningococcus; treponema pallidum
B-lactams
DOC for MRSA
glycopeptics
not great in CNS; entero-hepatic cycling; inhibit 30s subunit of ribosome
tetracyclines
don’t use in patients under 8 years old 2/2 bone teeth deposition
tetracyclines
photosensitivity + possibly hepatotox
tetracyclines
name one std and 2 tick diseases tx with doxycycline
Rickettsia
Chlamydia
Lyme
Rocky Mountain Spotted Fever
IV admin with low GI absorb and low VD
aminoglycosides
name a class besides tetracyclines that inhibit 30s
aminoglycosides
nephro+ototox
aminoglycosides
aerobic gram negative
aminoglycosides
macrolides target
60s subunit of ribosome
name member of macrolide class that can tx chlamydia and URIs
azithromycin
azithromycin can be given ….. route and is metabolized by …….
oral. biliary/liver
not given to kids below 18 yrs of age or pregnant women; achilles tendon rupture
FQNs
have two targets (gyrase and topoisomerase) with high Vd
FQNs
prostatitis, URI, 3rd gen can tx bone/joint infxn
FQNs
cipro is 2nd gen so 3rd generation specific example drug is …… (2 possible answers)
levoflox or moxi
FQNs excreted unchanged in urine except for one specific member
moxi
name a drug that can tx anaerobes including c. diff but you cant drink etoh with
metronidazole
name a major side effect of a class of drugs that inhibit folate metabolism in bacteria
rash (sulfonamides)
