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Flashcards in Antibiotics Deck (66):
1

Trimethoprim can be given safely in pregnancy. True or false?

False
- it inhibits folic acid synthesis

2

Avoid trimethoprim during which months of pregnancy?

First 3 months

3

What is trimethoprim commonly used to treat?

UTI

4

Trimethoprim treats a range of organisms. However, which organism does it not treat?

Pseudomonas

5

What are the components of co-trimoxazole

Sulphamethoxazole + trimethoprim

6

Which antibiotic carries a risk of developing Steven Johntson syndrome

Co-trimoxazole
- sulphamethoxazole part

7

Nitrofurantoin is commonly used to treat?

UTI

8

Nitrofurantoin can treat upper and lower UTI. True or false?

False
- only treats lower UTI

9

When should you avoid using nitrofurantoin?

Late pregnancy
Breast feeding
Children < 3 months

10

Nitrofurantoin treats a variety of organisms. However, name 2 organisms common in UTI that it does not treat?

Proteus
Pseudomonas

11

Amoxicillin is safe in pregnancy. True or false?

True

12

Cefalexin is safe to use in pregnancy. True or false?

True

13

Which type of organisms are lactose fermenters?

Coliforms

14

What is the function of ESBLs?

Makes bacteria resistant to all cephlasporins and most penicillins
- therefore, you are very restricted to which antibiotics are sensitive to the patient

15

If a patient has ESBLs what can you treat them with?

Nitrofurantoin
Meropenem

16

CPE are resistant to all meropenem. True or false?

True

17

Which organism's culture smells like burnt chocolte?

Proteus

18

Pseudomonas aeruginosa is a coliform. True to false?

False

19

Management of pseudomonas?

Ciprofloxacin

20

Antibiotic of choice for anaerobes?

Metronidazole

21

Which drug is used for gram -ve organisms if gentamicin is contra-indicated?

Astreolam

22

Carbapenems are active against ESBL producers. True or false?

True

23

Management of staph aureus

Flucloxacilin

24

Where do penicillins act?

Bacterial cell wall
-only work in gram +ve organisms

25

Penicillin contains a betalactam ring?

True

26

Penicillin is not safe in pregnancy. True or false?

False
- safe in pregnancy

27

Which 2 drugs make up co-amoxiclav

Amoxicillin + clavulanic acid
- beta lactamase inhibitor
- if organisms contain beta lactamase in order to break down the beta lactam ring then co-amoxiclav will still be effective as it inhibits the beta lactamase

28

What is the function of beta lactamase

Destroys the antibiotics beta lactam ring and makes the antibiotic ineffective

29

Name 3 antibiotic classes that contain a beta lactam ring in their structure

Penicillins
Carbapenems
Cephlasporins

30

What is the IV form of penicillin ?

Benzylpenicillin

31

Which antibiotic is used in MRSA?

Vancomycin

32

Give an example of a glycopeptide

Vancomycin

33

Name 3 macrolides

Erythromycin
Clarithromycin
Azithromycin

34

Which macrolide is safe in pregnancy?

Erythromycin

35

Name an example of an aminoglycoside

Gentamicin

36

Treatment of choice for coliforms?

Gentamicin

37

Cephlasporins are safe to use in pregnancy. True or false?

True

38

Name 2 tetracycline antibiotics

Clindamycin
Doxycycline

39

Name an example of a quinolone

Ciprofloxacin

40

Name the 4 C’s

Co-amoxiclav
Clindamycin
Ciprofloxacin - and all other quinolone
Cephlasporins

41

Alcohol can be taken with metronidazole. True or false?

False

42

What is the treatment of choice for a strep infection?

Penicillin

43

Sepsis - antibiotics

Amoxicillin (for gram +ve organisms) +
Metronidazole (for anaerobes) +
Gentamicin (for gram -ve organisms)

Antibiotics are for 10-14 days

44

COPD exacerbation. First line antibiotic

Amoxicillin 5 days

45

COPD exacerbation. 2nd line management

Doxycycline 5 days

46

Management of TB

2RIPE4RI
2 months rifampicin, isoniazid, pyrazinamide, ethambutol
4 months rifampicin, isoniazid

47

This drug stains bodily fluids orange

Rifampicin

48

This drug used in the treatment of TB can lead to optic problems

Ethambutol

49

Which drug used in the treatment of TB causes hepatitis and joint pains

Pyrazinamide

50

Which drug in the treatment of TB can result in neuropathies, hepatitis

Isoniazide

51

Management of epiglottitis

Ceftriaxone

52

Bordatella pertussis management

Macrolides
- only indicated in the first 21 days

53

Mild CAP (score 0-2) treatment

Amoxicillin (or doxycycline)

54

Severe CAP (3-5) management

Co-amoxiclav (IV) + clarithromycin OR
Co-amoxiclav (IV) + doxycycline

55

HAP management mild

Amoxicillin (oral) + metronidazole

56

HAP severe management

Amoxicillin (IV) + metronidazole + gentamicin

57

Management of most atypical pneumonia’s

Macrolides

58

Management of pneumocystis pneumonia

Co-trimoxazole

59

Management of chlamydial conjunctivitis

Topical oxytetracycline

60

Management of bacterial conjunctivitis

Chloramphenicol

61

Management of bacterial keratitis

Hourly drops of oflxacin

62

Staph aureus endocarditis management

IV flucloxacillin

63

Staph epidermidis (prosthetic valve) management

IV vancomycin
IV gentamicin
PO rifampicin

64

Strep viridans (sub acute) endocarditis management

IV amoxicillin
IV gentamicin

65

Management of MRSA infective endocarditis

IV gentamicin
PO rifampicin
IV vancomycin

66

Strep pyogenes management

Penicillin