Flashcards in Antibiotics Deck (66):
Trimethoprim can be given safely in pregnancy. True or false?
- it inhibits folic acid synthesis
Avoid trimethoprim during which months of pregnancy?
First 3 months
What is trimethoprim commonly used to treat?
Trimethoprim treats a range of organisms. However, which organism does it not treat?
What are the components of co-trimoxazole
Sulphamethoxazole + trimethoprim
Which antibiotic carries a risk of developing Steven Johntson syndrome
- sulphamethoxazole part
Nitrofurantoin is commonly used to treat?
Nitrofurantoin can treat upper and lower UTI. True or false?
- only treats lower UTI
When should you avoid using nitrofurantoin?
Children < 3 months
Nitrofurantoin treats a variety of organisms. However, name 2 organisms common in UTI that it does not treat?
Amoxicillin is safe in pregnancy. True or false?
Cefalexin is safe to use in pregnancy. True or false?
Which type of organisms are lactose fermenters?
What is the function of ESBLs?
Makes bacteria resistant to all cephlasporins and most penicillins
- therefore, you are very restricted to which antibiotics are sensitive to the patient
If a patient has ESBLs what can you treat them with?
CPE are resistant to all meropenem. True or false?
Which organism's culture smells like burnt chocolte?
Pseudomonas aeruginosa is a coliform. True to false?
Management of pseudomonas?
Antibiotic of choice for anaerobes?
Which drug is used for gram -ve organisms if gentamicin is contra-indicated?
Carbapenems are active against ESBL producers. True or false?
Management of staph aureus
Where do penicillins act?
Bacterial cell wall
-only work in gram +ve organisms
Penicillin contains a betalactam ring?
Penicillin is not safe in pregnancy. True or false?
- safe in pregnancy
Which 2 drugs make up co-amoxiclav
Amoxicillin + clavulanic acid
- beta lactamase inhibitor
- if organisms contain beta lactamase in order to break down the beta lactam ring then co-amoxiclav will still be effective as it inhibits the beta lactamase
What is the function of beta lactamase
Destroys the antibiotics beta lactam ring and makes the antibiotic ineffective
Name 3 antibiotic classes that contain a beta lactam ring in their structure
What is the IV form of penicillin ?
Which antibiotic is used in MRSA?
Give an example of a glycopeptide
Name 3 macrolides
Which macrolide is safe in pregnancy?
Name an example of an aminoglycoside
Treatment of choice for coliforms?
Cephlasporins are safe to use in pregnancy. True or false?
Name 2 tetracycline antibiotics
Name an example of a quinolone
Name the 4 C’s
Ciprofloxacin - and all other quinolone
Alcohol can be taken with metronidazole. True or false?
What is the treatment of choice for a strep infection?
Sepsis - antibiotics
Amoxicillin (for gram +ve organisms) +
Metronidazole (for anaerobes) +
Gentamicin (for gram -ve organisms)
Antibiotics are for 10-14 days
COPD exacerbation. First line antibiotic
Amoxicillin 5 days
COPD exacerbation. 2nd line management
Doxycycline 5 days
Management of TB
2 months rifampicin, isoniazid, pyrazinamide, ethambutol
4 months rifampicin, isoniazid
This drug stains bodily fluids orange
This drug used in the treatment of TB can lead to optic problems
Which drug used in the treatment of TB causes hepatitis and joint pains
Which drug in the treatment of TB can result in neuropathies, hepatitis
Management of epiglottitis
Bordatella pertussis management
- only indicated in the first 21 days
Mild CAP (score 0-2) treatment
Amoxicillin (or doxycycline)
Severe CAP (3-5) management
Co-amoxiclav (IV) + clarithromycin OR
Co-amoxiclav (IV) + doxycycline
HAP management mild
Amoxicillin (oral) + metronidazole
HAP severe management
Amoxicillin (IV) + metronidazole + gentamicin
Management of most atypical pneumonia’s
Management of pneumocystis pneumonia
Management of chlamydial conjunctivitis
Management of bacterial conjunctivitis
Management of bacterial keratitis
Hourly drops of oflxacin
Staph aureus endocarditis management
Staph epidermidis (prosthetic valve) management
Strep viridans (sub acute) endocarditis management
Management of MRSA infective endocarditis