Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

Pharmacology > Antibiotics > Flashcards

Antibiotics Flashcards

(67 cards)

Start Studying
1
Q

Which antibiotics act on DNA synthesis?

A

Quinolones

Folate acid antagonists

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Which antibiotics act on protein synthesis?

A

Aminoglycasides
Macrolides
Tetracyclines

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Which antibiotics act on cell wall synthesis?

A

Beta-lactams

  • penicillins
  • cephalosporins
  • carbapenems

Glycopeptides

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is an example of a quinolone?

A

Ciprofloxacin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What are the indications for ciprofloxacin?

A 
Superficial bacterial eye infection 
Corneal ulcer
Acute otitis externa 
Diabetic foot infection 
 Acute diverticulitis 
Respiratory tract infection 
UTI
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What are the routes of administration of ciprofloxacin?

A

Oral
IV
Eye drops

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is the mechanism of ciprofloxacin?

A

Inhibits DNA synthesis

  • interrupts DNA gyrase
  • DNA unable to unwind
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What are the side effects of ciprofloxacin?

A 
Loss of appetite
Constipation 
D+V
Prolonged QT 
Headache
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What are examples of folic acid antagonists?

A

Trimethoprim

Co-trimoxazole

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What are the indications of trimethoprim?

A

Respiratory tract infections
Shigellosis
Acute diverticulitis
UTI

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What are the routes of administration of trimethoprim?

A

Oral

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What is the mechanism of trimethoprim?

A

Folic acid needed for DNA synthesis

Antagonises folic acid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What are the side effects of trimethoprim?

A 
D+V
Nausea
Electrolyte imbalance
Skin reactions 
Fungal overgrowth
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What is co-trimoxazole?

A

Trimethoprim + Sulfamethoxazole

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is an example of an aminoglycoside?

A

Gentamicin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What are the indications for gentamicin?

A 
Bacterial eye infection 
Otitis externa 
Diabetic foot infection
Gram-positive endocarditis
Septicaemia
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

What are the routes of administration of gentamicin?

A

IV
IM
Eye drops
Ear drops

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

When is gentamicin contraindicated?

A

Myasthenia gravis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

What is the mechanism of gentamicin?

A

Inhibits protein synthesis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

What are the side effects of gentamicin?

A

Skin reactions

Tinnitus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

What are examples of a macrolide?

A

Clarithromycin

Erythromycin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

What are the indications for erythromycin?

A 
Infections with penicillin allergy 
Impetigo 
Cellulitis
CAP
Acute otitis media
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

What are the routes of administration of erythromycin?

A

Oral

IV

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

What are the side effects of erythromycin?

A

GI problems
Headache
Hearing impairment
Pancreatitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
What are the indications for clarithromycin?
``` Mild diabetic foot infection Leg ulcer infection Cellulitis Impetigo CAP/HAP Bronchiectasis exacerbation ```
26
What are the routes of administration of clarithromycin?
Oral | IV
27
What are the side effects of clarithromycin
GI problems Headache Hearing impairment Pancreatitis
28
What is an example of a tetracycline?
Doxycycline
29
What are the indications for doxycycline?
``` Acute sinusitis HAP Exacerbation of bronchiectasis COPD exacerbation Cellulitis Syphilis PID Lyme disease ```
30
What is the route of administration of doxycycline?
Oral
31
What are the side effects of doxycycline?
``` Angioedema GI problems Henoch-Schonlein purpura Hypersensitivity SLE exacerbation ```
32
What are the types of B-lactams?
Penicillins Cephalosporins Carbapenems
33
What are examples of a penicillin?
Amoxicillin Flucloxacillin Co-amoxiclav
34
What are indications for amoxicillin?
Bacterial infections CAP Acute exacerbations Acute otitis media H pylori eradication
35
What are the routes of administration for amoxicillin?
Oral IV IM
36
What is the mechanism of action of amoxicillin?
Inhibits cell wall synthesis - bactericidal
37
What are the side effects of amoxicillin?
``` Allergy D+V Nausea Skin reaction Thrombocytopenia ```
38
What are the indications for flucloxacillin?
Stapylococci infections Impetigo Cellulitis Osteomyelitis
39
What are the routes of administration for flucloxacillin?
Oral IV IM
40
What is the mechanism of flucloxacillin?
Inhibits cell wall synthesis - bactericidal
41
What are the side effects of
``` Allergy D+V Nausea Skin reaction Thrombocytopenia ```
42
What makes up co-amoxiclav?
Amoxicillin + clavulanic acid
43
What is the mechanism of clavulanic acid?
Beta-lactamase inhibitor Stops beta-lactam ring in amoxicillin being broken down by bacteria
44
What is an example of a cephalosporin?
Ceftriaxone
45
What are the indications for ceftriaxone?
``` CAP HAP Cellulitis Bacterial meningitis Syphilis ```
46
What are the routes of administration for ceftriaxone?
IV | Deep IM
47
What is the mechanism of ceftriaxone?
Inhibits cell wall synthesis
48
What are the side effects of ceftriaxone?
``` Abdo pain D+V Eosinophilia Headache Thrombocytopenia ```
49
What is an example of a carbapenem?
Meropenem
50
What are the indications for meropenem?
Aerobic + anaerobic gram positive + negative infections
51
What is the route of administration for meropenem?
IV
52
What is the mechanism of meropenem?
Inhibits cell wall synthesis
53
What are the side effects of meropenem?
``` Abdo pain D+V Headache Pain Skin reactions ```
54
What are examples of glycopeptides?
Vancomycin | Teicoplanin
55
What are the indications for vancomycin?
C.diff infection Skin/soft tissue infections CAP/HAP
56
What is the route of administration of vancomycin?
IV
57
What is the mechanism of action of vancomycin?
Inhibits cell wall synthesis
58
What are the side effects of vancomycin?
``` Neutropenia Renal failure Fever Nausea Tinnitus ```
59
What are the indications for teicoplanin?
C.diff infection Gram positive bacteria Soft tissue infections
60
What are the routes of administration of teicoplanin?
IV | Oral
61
What is the mechanism of action of teicoplanin?
Inhibits cell wall synthesis
62
What are the side effects of teicoplanin?
Fever Pain Skin reactions
63
What are indications of metronidazole?
``` Anaerobic infections H.pylori eradication Soft tissue infections Bacterial vaginosis Rosacea ```
64
What are the routes of administration of metronidazole?
Oral IV Topical
65
What is the mechanism of metronidazole?
Prevents growth of bacteria
66
What are the side effects of metronidazole?
Dry mouth Myalgia Nausea Skin reactions
67
Which antibiotics need monitoring?
Aminoglycosides | Vamcomycin

Pharmacology (27 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions