Antibiotics

Question 1

Sulfamethoxazole

Answer 1

Sulfonamides

Question 2

MOA is Bacteriostatic, prevents synthesis of folic acid

Answer 2

Sulfonamides

Question 3

Used to treat UTIs and reduce pain associated with UTIs

Answer 3

Sulfamethoxazole

Question 4

Class of Penicillin: oxacillin, nafcillin, methicillin, dicloxacillin, cloxacillin?

Answer 4

Penicillinase-resistant penicillins

Question 5

Class of penicillins: piperacillin, ticracillin, carbenicillin, mezlocillin?

Answer 5

Extended-spectrum penicillins

Question 6

Class of penicillins: amoxicillins, ampicillin, bacampicillin?

Answer 6

Aminopenicillins

Question 7

Class of penicillins: penicillin G, penicillin V potassium?

Answer 7

Natural penicillins

Question 8

MOA of penicillins

Answer 8

Bactericidal: inhibit cell wall synthesis

Question 9

What are the chemicals that are developed to inhibit beta-lactamases in penicillins?

Answer 9

Clavulanic acid
Tazobactam
Sulbactam

Question 10

Penicillin-beta-lactamase inhibitor combination drugs

Answer 10

Amoxicillin + clavulanic acid = Augmentin
Ticarcillin + clavulanic acid = Timentin
Ampicillin + sulbactam = Unasyn
Piperacillin + tazobactam = Piptaz

Question 11

MOA is disruption of bacterial cell wall synthesis

Answer 11

Penicillin

Question 12

Structurally and pharmacologically related to penicillins. Semisynthetic derivatives from fungus.

Answer 12

Cephalosporins

Question 13

Generation of cephalosporins: Cephalexin?

Answer 13

First gen

Question 14

Generation of cephalosporins: Cefazolin?

Answer 14

First gen

Question 15

Generation of cephalosporins: Cefuroxime?

Answer 15

Second gen

Question 16

Generation of cephalosporins: Cefaclor?

Answer 16

Second gen

Question 17

Only oral preparation in third gen cephalosporins

Answer 17

Cefixime

Question 18

Cephalosporin that treats CNS infections

Answer 18

Ceftriaxone (Rocephin)

Question 19

Cephalosporin generation that has increase activity against Haemophilus influenzae

Answer 19

Second generation

Question 20

Cephalosporin that is used for difficult-to-treat organisms such as Pseudomonas spp.

Answer 20

Ceftazidime

Question 21

Newest cephalosporin that has broader spectrum of antibacterial activity especially against gram positive bacteria

Answer 21

Cefepime (fourth gen)

Question 22

Most potent group of cephalosporins against gram negative

Answer 22

Third generation

Question 23

Antibiotics used for tx for suspected MDR bacteria and ESBL producing E. coli

Answer 23

Carbapenems

Question 24

Cephalosporin group: Imipenem?

Answer 24

Carbapenem (beta-lactam)

Question 25

Cephalosporin group: Meropenem?

Answer 25

Carbapenem (beta-lactam)

Question 26

A glycopeptide antibiotic that acts on the cell wall and indicated in treating MRSA and MRSE

Answer 26

Vancomycin

Question 27

Antibiotic group: Doxycycline?

Answer 27

Tetracyclines

Question 28

Antibiotic group: Monocycline?

Answer 28

Tetracyclines

Question 29

MOA of Tetracyclines

Answer 29

Bacteriostactic: inhibit protein synthesis

Question 30

Antibiotic group that is natural and semi synthetic which is obtained from Streptomyces

Answer 30

Tetracyclines

Question 31

One of its side effects is the reatrdation of fetal skeletal development if taken during pregnancy.

Answer 31

Tetracyclines

Question 32

Antibiotic group: Gentamicin

Answer 32

Aminoglycosides

Question 33

Antibiotic group: Tobramycin?

Answer 33

Aminoglycosides

Question 34

Antibiotic group: Streptomycin

Answer 34

Aminoglycosides

Question 35

3 most common (systemic) Aminoglycosides.

Answer 35

Gentamicin, Tobramycin, Amikacin

Question 36

Antibiotic group: Levofloxacin?

Answer 36

Quinolones

Question 37

Antibiotic group: Ciprofloxacin?

Answer 37

Quinolones

Question 38

MOA of Quinolones

Answer 38

Bactericidal: alter DNA of bacteria causing its death

Question 39

Group of antibiotics that causes serious toxicities such as nephrotoxicity and ototoxicity (eighth cranial nerve)

Answer 39

Aminoglycosides

Question 40

Most antibiotics should be taken on an empty stomach to attain faster absorption except:

Answer 40

Erythromycin Nitrofurantoin Cefuroxime

Question 41

Common side effects include bone marrow suppression and causes a condition in young children called gray baby syndrome.

Answer 41

Chloramphenicol

Question 42

MOA includes binding to the 50s rRNA of the large bacterial ribosome unit

Answer 42

Clindamycin

Question 43

MOA includes binding to the 30s rRNA of the large bacterial ribosome unit

Answer 43

Macrolides