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Antibiotics Flashcards

(67 cards)

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1
Q

chlamydia

A

doxycycline or azithromycin

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2
Q

candidiasis

A

fluconazole, amphotericin

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3
Q

bacterial vaginosis

A

metronidazole (pregnancy safe) or clindamycin

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4
Q

trichomoniasis

A

metronidazole

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5
Q

gonorrhoea

A

ceftriaxone + azithromycin

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6
Q

cystitis (lower UTI)

A

oral nitrofurantoin or trimethoprim

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7
Q

pyelonephritis (upper UTI)

A

IV cephalosporin/quinolone/gentamicin

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8
Q

salmonella typhi

A

ciprofloxacin if outside indian subcontinent, otherwise ceftriaxone

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9
Q

meningococcal

A

IM or IV benzylpenicillin, household/close contacts rifampicin

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10
Q

impetigo

A

localised: fusidic acid 2% cream or mupiricin 2% cream
widespread: flucloxacillin or erythromycin

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11
Q

erysipelas

A

benzylpenicillin + flucloxacillin

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12
Q

cellulitis

A

benzylpenicillin + flucloxacillin

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13
Q

enteric fever

A

azithromycin +/- ceftriaxone

dexamethasone if CNS involvement

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14
Q

dermatopytosis

A

superficial mycoses: topical azole antifungal or terbinofine + topical nystaxin + amphotericin
tinea capitis: grisecfulrin, terbinafine, itraconazole
nail infection: systemic, terbinafine, itraconazole

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15
Q

cryptococcus neoformans

A

amphotericin + flucytosine, fluconazole

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16
Q

histoplasmosis

A

amphotericin, itraconazole

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17
Q

cholera

A

doxycycline or tetracycline

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18
Q

shigella

A

ciprofloxacillin, azithromycin

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19
Q

campylobacter

A

macrolide, doxycycline, quinolone

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20
Q

giardiasis

A

metronidazole, tinidazole, albenazole

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21
Q

cryptosporidium

A

nitazoxamide

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22
Q

amoebiasis

A

metronidazole/tinidazole, diloxanide furoate for gut cysts

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23
Q

nematodes

A

mebendazole (roundworm, hookworm, whipworm)
albendazole (ascariasis, hookworm, strongyloides)
ivermectin (strongyloides, ascariasis)
pyrantel pamoate (threadworm, roundworm, hookworm)
piperazine (ascariasis, pregnancy)

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24
Q

taemiasis (tapeworms)

A

praziquantel, niclosamide

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25
listeria infection
ampicillin + gentamicin
26
clostridium perfringens
protein synthesis inhibitors
27
diptheria
benzylpenicillin/erythromycin
28
resistant staph aureus
vancomycin (MRSA), teicoplanin | oral agents: clindamycin, co trimoxazole, doxycycline, linezolid
29
strep agalactiene
penicillin, macrolide, cephalosporin, chloramphenicol
30
neisseria
benzylpenicillin/ceftriaxone
31
moraxella catarrhalis
macrolide, cephalosporin
32
haemophilus influenzae
amoxicillin, macrolide, cephalosporin, chloramphenicol, rifampicin
33
clostridium difficile
moderate-mild: metronidazole severe: vancomycin or fidaxomicin non responders: high dose vancomycin + IV metronidazole fidaxomicin, IVg recurrence: vancomycin, fidaxomicin, faecal transplanr
34
hepatitis B
entecavir + tenofovir
35
hepatitis C
gamma PEGylated alpha interferon + ribavirin
36
HSV (herpes)
aciclovir
37
VZV
aciclovir (safe in pregnancy)/valaciclovir
38
CMV
ganciclovir, valganciclovir | foscarnet, cidofovir
39
HIV
PEP: truvada + vategravir, short term CART ART: NRTI backbone (tenofovir, truvada + kinexa), protease inhibitors (azamativir, darunavir), NNRTI (nipivirine, efavirenz)
40
pneumocystis jirovecii
IV co trimoxazole, 2nd line clindamycin, pentamidine, atoragrene
41
influenza
oseltamivir, zanamivir
42
invasive pulmonary aspergillosis
antifungals, amphotericin B, VFend
43
malaria
uncomplicated: ACT, dihydro ortemistrin - piperaquine severe: artesumate, quinine prophylaxis: chloroquine +/- proguanil chloroquine resistance: mefloquine or doxycycline or atovaquone - proguanil combo
44
bacterial meningitis
benzylpenicillin or ceftriaxone
45
meningococcal meningitis
IV penicillin @ GP, high dose ceftriaxone prior to LP | discharge w/ rifampicin or ciprofloxacin
46
pneumococcal meningitis
high dose ceftriaxone
47
haemophilus influenzae meningitis
ceftriaxone | prophylaxis w/ rifampicin for close contacts
48
listeria monocytogenes meningitis
IV ampicillin
49
neonatal meningitis
group B strep: benzylpenicillin + amoxicillin E coli: cefotaxime listeria monocytogenes: ampicillin + gentamicin
50
viral meningitis
IVg + aciclovir IV for HSV
51
necrotising fasciitis
flucloxacillin: staph aureus + other gram +ves gentamicin: gram +ve + some gram -ves clindamycin: anaerobic + gram +ve
52
botulism
antitoxin, benzylpenicillin, metronidazole
53
tetanus
metronidazole | spasm: diazepam/lorazepam/midazolam, IV magnesium sulfate, baclofen
54
schistosomiasis
2x doses praziquantel
55
echinococcosis
triclabendazole
56
pertussis
macrolide e.g. clarithromycin
57
scabies
permethrin 5% dermal cream malathion (2nd line) oral ivermectin (severe)
58
leprosy
multibacillary: rifampicin, dapsone, clofazimine paucibacillary: rifampicin, dapsone
59
TB
``` rifampicin 2 months intensive, 4 months continuous isoniazid (same as above) pyrazinamide 2 months intensive ethambutol (same as above) latent: 3 months I + R or 6 months I ```
60
lyme disease
ceftriaxone, IV benzylpenicillin or doxycycline
61
rickettsial disease
doxycycline, azithromycin, chloramphenicol
62
leishmaniasis
amphotericin
63
anthrax
quinolone/doxycycline, ciprofloxacin + clindamycin or linezolid
64
brucellosis
doxycycline + rifampicin or gentamicin | + co trimoxazole for CNS disease
65
Q fever
doxycycline
66
leptospirosis (weil's disease)
doxycycline if mild, IV penicillin if severe
67
toxoplasmosis
pyrimethamine + sulfaclinazine + folic acid

Infection (4 decks)

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