Antibiotics Cautions,contraindications And MHRA Warnings

Question 1

Which antibiotics need to be taken before food/on an empty stomach? (Label 23 and 22)
DROP FAT!!!

Answer 1

Demeclocycline
Rifampicin (label 22/23)
Oxytetracycline
PhenoxymethylPenicillin
Flucloxacillin
Ampicillin
Tetracycline

Question 2

With/After food (label 21) - take with food or just after food or meal
MY NICE PASTA

Answer 2

—Metronidazole
— Nitrofuratoin
—Pivmeclillinam

Question 3

Antibiotics with milk? Does like milk (label 6)

Answer 3

Doxycycline
Lymecycline
Minocycline
(All tetracyclines except ciprofloxicin)

Question 4

Do not taken with milk - Label 7

Answer 4

Ciprofloxacin
Demeclocycline
Oxytetracycline
Tetracycline

C.DOT

Question 5

What does label 5 state?

Answer 5

Do not take indigestion remedies 2 hours before or after this medicine

(Used with enetric coated tablets) - Gabapentin

Question 6

Label Number 6

Answer 6

Do not take indigestion remedies or medicines containing iron or zinc, 2 hours before or after taking this medication

When is it used - preparations containing ofloxacin and some other quinolones, doxycycline, lymecycline,minocycline and penicillamine

Question 7

Label number 7

Answer 7

Do not take milk,indigestion remedies or medicines containing iron or zinc, 2 hours before or after you take this medicine

• preps containing ciprofloxicin,norfloxicin or tetracyclines that chelate calcium,iron,magnesium, zinc and are thus less available for absorption

Question 8

Label Number 22

Answer 8

Take 30-60 mins before food

• preparations who’s absorption is improved eg. Lansoprazole

Question 9

Label 23

Answer 9

Take the medicine when your stomach is empty. This means an hour before food

Most oral antibiotics, absorption reduced by food and acid in the stomach

Question 10

Which antibiotics can be given in pregnancy?

PEC ‘C’ chest

Answer 10

Penicillins
Erythromycin - make sure benefits outweigh the risks
Cephalopsorins
Clindamycin

Question 11

Avoid in pregnancy

Answer 11

• Tetracyclines
• Aminoglycosides
• Macrolides - except erythromycin
• Co- trimoxazole
• Rifampicin
• Metroniodazole
• Quinolones
• Nitrofurantoin - can but has conditions

Question 12

Photosensitive

Answer 12

Doxycycline
Demeclocycline (most common than with other tetracyclines!)

Question 13

Important safety information - warning information

Answer 13

• Flucloxacillin (Cholestatic jaundice and hepatitis)
• Co-amoxiclav (Cholestatic Jaundice)
• Linezolid (Blood disorders and optic neuropathy - remember eye lid)
• Co- trimazole - Stevenson Johnson syndrome - severe allergic skin reactions and blood disorders
• Quinolones (tendon damage, arthropathy - joint problems in children and convulsions)

Question 14

Antibiotic urine colouring

Answer 14

• Rifampicin
• Nitrofuratoin
• Colour = brown/ orange

Question 15

What are the signs of a blood disorder

Answer 15

Sore throat, Fever,Malaise, rash, mouth ulcers, bruising and bleeding

Question 16

Which antibiotics cause blood disorders?

Answer 16

• trimethoprim
• co-trimazole
• linezolid
• Gentamicin
• Vancomycin

Question 17

Important contraindications-

Answer 17

• pencillins- penicillin allergy
• Tetracyclines - Children under 12 and pregnant women
• Quinolones -History if tendon disorders related to quinolones use
• Aminoglycosides - Myasthaenia gravis