ANTIBIOTICS DRUGS Flashcards
(10 cards)
Also known as prokaryotes they are single-celled organisms that lack a true nucleus membrane.
BACTERIA
It is a substance that inhibits bacterial growth or kills bacteria and other microorganisms.
ANTIBACTERIAL DRUGS
What are the mechanisms of antibacterial action?
- inhibition of bacterial cell-wall synthesis
- alteration of membrane permeability
- inhibition of protein synthesis
- inhibition of the synthesis of bacterial RNA and DNA
- interference with metabolism within cell
The development of a new infection as a result of the elimination of normal flora by an antibiotic is referred to as what?
Suprainfection
What considerations are needed when selecting an antibiotic?
Infecting Organism
Organism’s Sensitivity and Resistance
Host Defenses (competent immune function)
Site of Infection
What is the most serious adverse effect of Vancomycin?
Ototoxicity and nephrotoxicity
What is the correct time to obtain a trough level of gentamicin?
30 minutes before the next dose.
The antibiotic class of choice for Penicillin-allergic patients is
Macrolides
What is selective toxicity?
Causes greater harm to microorganism than to the host
The nurse is providing discharge teaching to a patient who is being sent home on oral tetracycline (Sumycin). What instructions should the nurse include?
Take the drug on an empty stomach