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Selfmade > Antibodies > Flashcards

Antibodies Flashcards

1
Q

Antinuclear Antibody (ANA)

9 possible Answers

A
  1. SLE
  2. Drug Induces Lupus, Sjörgen
  3. Polymyositis and Dermatomyositis
  4. Juvenile Idiopathic Arthritis, Raynauds
  5. Mixed Connective Tissue
  6. Autoimmune Hepatitis
  7. Scleroderma or Systemic Sclerosis
  8. T1 Diabetes
  9. Psoriasis.
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2
Q

Antineutrophil Cytoplasmic Antibodies (ANCA)

A

cANCA or Antiproteinase 3 PR3-ANCA:
Granulomatosis with polyangiitis aka Wegener Granulomatosis

pANCA or Myeloperoxidase MPO ANCA:
Microscopic Polyangiitis
Eosinophilic Granulomatosis with polyangiitis aka Churg Strauss Polyarteritis Nodosa
Ulcerative Colitis

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3
Q

Anti-dsDNA

A

SLE

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4
Q

Anticentromere Antibody (ACA and Anti Scl 70)

A

Scleroderma- Diffuse and Limited aka CREST

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5
Q

CREST

A

Calcinosis
Raynauds
Esophageal Dysfunction
Sclerodactyly
Telangiectasia

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6
Q

Antihistone Antibodies (AHs)

A

SLE
Drug induces Lupus
Juvenile Rheumatoid Arthritis
Rheumatoid Arthritis

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7
Q

Cyclin Citrullinated Peptide (CCP)

A

Rheumatoid Arthritis

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8
Q

Rheumatoid Factor (RF)

A

Rheumatoid Arthritis or Sjörgen

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9
Q

Anti Jo 1

A

Polymyositis

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10
Q

Anti SS A (Ro) and Anti SS B (La)

A

Sjörgen

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11
Q

Anti Smith (Sm)

A

SLE

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12
Q

Anti Tissue Transglutaminase and Anti Gliadin

A

Celiac

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13
Q

Antiphospholipid Antibodies

A

APLA- Lupus- Young Women with multiple failed pregnancies.

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14
Q

Diabetes related Autoantibodies

A

Islet Cell Cytoplasmic Autoantibodies
Glutamic Acid Decarboxylase Autoantibodies
Insulinoma Associated 2 Autoantibodies
Insulin Autoantibodies
Zinc Transporter 8 Autoantibodies

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15
Q

Intrinsic Factor Antibodies

A

Pernicious Anemia

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16
Q

Thyroid Antibody

A

Graves Disease

17
Q

Antimitochondrial Antibody

A

Primary Biliary Cholangitis

18
Q

Smooth Muscle Antibody and F actin Antibody

A

AI Hepatitis

19
Q

Acetylcholine Receptor Antibody

A

Myasthenia Gravis

20
Q

Anti Glomerular Basement Membrane (GBM)

A

Goodpasture Syndrome

21
Q

SLE Antibodies

A

ANA
Anti dsDNA
AHA
Anti Sm (Smith)

22
Q

Antibodies in pregnant mom that may affect the fetus:

A
  1. Graves Disease (Anti-TSH)- Fetal Thyroid Destruction
  2. Sjrögen (Anti-Ro)- Fetal Heart Block
  3. Myasthenia Gravis (Anti-postsynaptic ACh Receptor)- Fetal Arthrogryposis
  4. Maternal Antobodies against surface platelets- Fetal Hemorrhage

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