Antibody Characteristics

Question 1

ABO

Answer 1

naturally occurring, clinically significant, cause in vitro hemolysis

Question 2

Lewis

Answer 2

naturally occurring, can react at any phase of testing, detection ENHANCED by enzyme treatment of test cells, bind complement, cause in vitro hemolysis

Question 3

P1

Answer 3

naturally occurring, cold antibody, can cause in vitro hemolysis

Question 4

MN

Answer 4

naturally occurring

Question 5

LUa

Answer 5

naturally occurring

Question 6

Rh

Answer 6

clinically significant, warm antibodies, detection ENHANCED by enzyme treatment of test cells, Rh other than D, MNS, Duffy, Kidd show dosage

Question 7

Kell

Answer 7

clinically significant, warm antibodies, usually only react in AHG (not IS)

Question 8

Duffy

Answer 8

Clinically significant, warm antibodies, usually only react in AHG (not IS), NOT DETECTED by enzyme treatment of test cells

Question 9

Kidd

Answer 9

clinically significant, warm antibodies, usually only react in AHG (not IS), detection ENHANCED by enzyme treatment of test cells, bind complement, cause in vitro hemolysis, labile in vivo and in vitro, common cause of delayed transfusion reaction (anamnestic response)

Question 10

SsU

Answer 10

clinically significant

Question 11

M

Answer 11

cold antibody, NOT DETECTED by enzyme treatment of test cells

Question 12

N

Answer 12

cold antibody, NOT DETECTED by enzyme treatment of test cells

Question 13

I

Answer 13

bind complement

Question 14

Vell

Answer 14

cause in vitro hemolysis

Question 15

Anti-p (IGG)

Answer 15

associated with paroxysmal nocturnal hemoglobinuria