Anticoagulant (direct thrombin inhibitors) Flashcards

1
Q

Prototype

A

Dabigatran

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2
Q

MOA

A

inhibits thrombus formation by directly inhibiting thrombin formation

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3
Q

Primary use

A

Reduce CVA and embolism risk with non valve A fib

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4
Q

side effects

A

Bleeding, GI discomfort

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5
Q

Considerations

A

stop 1-2 days before surgery
don’t take with NSAIDs or aspirin
don’t take missed dose within 6 hrs of missed dose

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