Anticoagulants

Question 1

Administered by oral route

Answer 1

warfarin clopidogrel

Question 2

bruising, URTI, rash, puritis, flu-like symptoms, dizziness

Answer 2

clopidogrel

Question 3

category B

Answer 3

lepirudin, clopidogrel

Question 4

weight-based dosing, no aPTT monitoring, sq route only

Answer 4

low-molecular-weight heparins

Question 5

protamine sulfate

Answer 5

heparin antidote

Question 6

inhibited anticoagulation with nicotine, tetracyclines, antihistamines, digoxin

Answer 6

heparin

Question 7

osteoporosis is an adverse effect

Answer 7

warfarin and heparin

Question 8

PT/INR monitor

Answer 8

warfarin

Question 9

aPTT monitor

Answer 9

heparin and lepirudin

Question 10

do not breast feed

Answer 10

aminocaproic acid and lepirudin

Question 11

acute coronary syndrome and percutaneous coronary intervention indications

Answer 11

abciximab

Question 12

back and chest pain, hypotension, bleeding

Answer 12

adverse effects of abciximab

Question 13

elevate head of bed and keep limb straight when femoral artery access is used

Answer 13

abciximab (ReoPro)

Question 14

restore IV catheter patency

Answer 14

alteplase

Question 15

enhanced hepatic degradation with IV nitroglycerin

Answer 15

alteplase

Question 16

keep patient in bed

Answer 16

alteplase

Question 17

transient dysrhythmias, angioedema, intracranial bleeding

Answer 17

alteplase

Question 18

aplastic anemia, postoperative cardiac surgery, hepatic cirrhosis, certain carcinomas

Answer 18

indications for aminocaproic acid

Question 19

hypercoagulation with estrogens and oral contraceptives

Answer 19

aminocaproic acid

Question 20

bradycardia, hypotension, myopathy, rhabdomyolysis

Answer 20

amicar

Question 21

plavix

Answer 21

clopidogrel

Question 22

contraindications: history of CVA in last 3 months, active bleeding, severe HTN, intracranial neoplasm, AV malformation

Answer 22

aminocaproic acid and alteplase

Question 23

usually in combination with aspirin (ASA) and heparin

Answer 23

abciximab GP IIB/IIIA inhibitors

Question 24

affected by drugs that inhibit or increase hepatic metabolic enzymes

Answer 24

clopidogrel

Question 25

evaluate unexplained fever/infection

Answer 25

plavix

Question 26

irreversible binding and anticoagulant effect lasts as long as one week

Answer 26

aspirin

Question 27

avoid high fat diet

Answer 27

warfarin

Question 28

category X

Answer 28

warfarin

Question 29

sulfite sensitivity and severe thrombocytopenia contraindicated

Answer 29

heparin

Question 30

for evolving MI, unstable angina, DVT, prophylaxis, acute thromboembolic disorders

Answer 30

heparin

Question 31

peripartum patient precaution

Answer 31

heparin

Question 32

long shelf life and 10x less HIT

Answer 32

low-molecular-weight heparins

Question 33

for nasal congestion and hypotension

Answer 33

alpha 1 agonists

Question 34

for cardiac arrest, heart failure, shock

Answer 34

beta 1 agonist

Question 35

receptor drug for hypertension

Answer 35

alpha 2 agonist

Question 36

receptor drug for asthma and preterm labor

Answer 36

beta 2 agonist

Question 37

receptor drug for hypertension and benign prostatic hyperplasia

Answer 37

alpha1 antagonist

Question 38

another receptor drug for hypertension, angina, cardiovascular disease

Answer 38

beta antagonist, blocker