Anticoagulation Flashcards

1
Q

High risk PE Initial treatment

A

Thrombolysis

UFH

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2
Q

Acute PE

A

LMWH/fondaparinux) or rivaroxaban for 5 days

  • Transition to VKA once INR 2-3 for 24 hrs
  • Continue for 3 months if provoked (surgery)
  • 3+ months if unprovoked
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3
Q

PE Associated w/ hypotension and/or shock

A
  • UFH
  • Thrombolytic therapy
  • Thrombolysis contraindicated - catheter embolectomy
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4
Q

PE w/ active cancer or pregnancy

A

LMWH, for more than 3 months

- continue at least 6 wks post partum

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5
Q

PE w/ CrCl < 30 mL/min

A

UFH

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6
Q

PE in children

A

UFH/LMWH, with LMWH or VKA long-term

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7
Q

Direct Anti-Xa

A
  • Rivaroxaban (Xarelto)
  • Apixaban (Eliquis)
  • Edoxaban (Savaysa)
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8
Q

Direct Anti-IIa

A

Dabigatran (Pradaxa)

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9
Q

NOAC - no renal adjustment

A
  • Apixaban (Eliquis)
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10
Q

NOAC over 15mg take with food

A

Rivaroxaban (Xarelto)

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