Anticoagulation Introduction Flashcards

(43 cards)

1
Q

ADP

A

Adenosine diphosphate

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2
Q

aPTT

A

activated partial thromboplastin time

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3
Q

COX

A

Cyclooxygenase

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4
Q

DOAC

A

direct oral anticoagulant

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5
Q

DVT

A

deep vein thrombosis

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6
Q

FFP

A

frozen fresh plasma

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7
Q

INR

A

international normalized ratio

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8
Q

LBS

A

lysine binding sites

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9
Q

LMWH

A

low molecular weight heparin

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10
Q

MOA

A

mechanism of action

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11
Q

NO

A

nitric oxide

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12
Q

PAR-1

A

protease-activated receptor-1

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13
Q

PCC

A

prothrombin complex concentrate

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14
Q

PE

A

pulmonary embolism

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15
Q

PGE2

A

prostaglandin E2

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16
Q

PGI2

A

prostaglandin I2

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17
Q

PT

A

prothrombin time

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18
Q

TFPI

A

tissue factor pathway inhibitor

19
Q

TP

A

thromboxane receptor

20
Q

tPA

A

tissue plasminogen activator

21
Q

TxA2

A

thromboxane A2

22
Q

uPA

A

urinary plasminogen activator

23
Q

VASP

A

vasodilator-stimulated phosphoprotein

24
Q

vWF

A

Von Willebrand Factor

25
Name the 7 natural anticoagulants
26
Name the target(s) for each natural anticoagulant agent
27
What prevents blood clotting in the normal healthy vascular system?
28
At what platelet count is a patient at an elevated risk of bleeding? At what platelet count is a patient at risk for spontaneous bleeding?
29
Draw platelet formation at each of the following states: Normal, Adhesion, Activation, Aggregation
30
Draw the clotting cascade diagram
31
Draw the flow chart for a platelet-fibrin thrombus formation
32
Name the anticoagulants and the factors they inhibit
33
Draw the antiplatlet agent diagram
34
Draw the cyclo-oxygenate platelet activation diagram
35
Draw the clot lysis diagram
36
List the intravenous and oral anticoagulants
37
What agents reverse the oral anticoagulants?
38
List the IV DTI anticoagulants
Argatroban Bivalirudin
39
List the oral DOACs
Apixaban Bextrixaban Edoxaban Rivaroxaban
40
List the clot busting medications
Alteplace Streptokinase
41
Praxbind generic
Idarucizumab
42
Andexxa generic
Andexanet alpha
43
List the GP2B/3A inhibitors