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pharmacy > Antidiabetics > Flashcards

Antidiabetics Flashcards

1
Q

Gliclazide

A

Sulfonylurea

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2
Q

Glipizide

A

Sulfonylurea

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3
Q

Glimepiride

A

Sulfonylurea

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4
Q

Glibenclamide

A

Sulfonylurea

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5
Q

Tolbutamide

A

Sulfonylurea

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6
Q

Sulfonylurea MOA

A

Increases pancreatic insulin secretion

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7
Q

Metformin MOA

A

Decreases gluconeogenesis. Increases peripheral utilisation of insulin

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8
Q

Canagliflozin

A

SGLT-2 Inhibitor

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9
Q

Dapagliflozin

A

SGLT-2 Inhibitor

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10
Q

Empagliflozin

A

SGLT-2 Inhibitor

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11
Q

SGLT-2 Inhibitor MOA

A

Reduces glucose reabsorption in the kidneys

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12
Q

Sitagliptin

A

DPP4 Inhibitor

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13
Q

Alogliptin

A

DPP4 Inhibitor

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14
Q

Vildagliptin

A

DPP4 Inhibitor

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15
Q

Saxagliptin

A

DPP4 Inhibitor

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16
Q

Linagliptin

A

DPP4 Inhibitor

17
Q

DPP4 Inhibitor MOA

A

Increases insulin secretion, decreases glucagon secretion

18
Q

Pioglitazone MOA

A

Reduces peripheral insulin resistance

19
Q

Exenatide

A

GLP-1 Mimetic

20
Q

Liraglutide

A

GLP-1 Mimetic

21
Q

Semaglutide

A

GLP-1 Mimetic

22
Q

Dulaglutide

A

GLP-1 Mimetic

23
Q

GLP-1 Mimetic MOA

A

Increases insulin secretion, reduces glucagon secretion, delays gastric emptying

24
Q

Acarbose MOA

A

Delays digestion of starch and sucrose

25
Q

Repaglinide

A

Meglitinide

26
Q

Nateglinide

A

Meglitinide

27
Q

Meglitinide MOA

A

Increases pancreatic insulin secretion (same as sulfonylureas although with less hypoglycaemia)
Not licensed for any other combination other than metformin

pharmacy (11 decks)

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