Antidiabetics Flashcards

(27 cards)

1
Q

Gliclazide

A

Sulfonylurea

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2
Q

Glipizide

A

Sulfonylurea

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3
Q

Glimepiride

A

Sulfonylurea

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4
Q

Glibenclamide

A

Sulfonylurea

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5
Q

Tolbutamide

A

Sulfonylurea

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6
Q

Sulfonylurea MOA

A

Increases pancreatic insulin secretion

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7
Q

Metformin MOA

A

Decreases gluconeogenesis. Increases peripheral utilisation of insulin

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8
Q

Canagliflozin

A

SGLT-2 Inhibitor

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9
Q

Dapagliflozin

A

SGLT-2 Inhibitor

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10
Q

Empagliflozin

A

SGLT-2 Inhibitor

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11
Q

SGLT-2 Inhibitor MOA

A

Reduces glucose reabsorption in the kidneys

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12
Q

Sitagliptin

A

DPP4 Inhibitor

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13
Q

Alogliptin

A

DPP4 Inhibitor

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14
Q

Vildagliptin

A

DPP4 Inhibitor

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15
Q

Saxagliptin

A

DPP4 Inhibitor

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16
Q

Linagliptin

A

DPP4 Inhibitor

17
Q

DPP4 Inhibitor MOA

A

Increases insulin secretion, decreases glucagon secretion

18
Q

Pioglitazone MOA

A

Reduces peripheral insulin resistance

19
Q

Exenatide

A

GLP-1 Mimetic

20
Q

Liraglutide

A

GLP-1 Mimetic

21
Q

Semaglutide

A

GLP-1 Mimetic

22
Q

Dulaglutide

A

GLP-1 Mimetic

23
Q

GLP-1 Mimetic MOA

A

Increases insulin secretion, reduces glucagon secretion, delays gastric emptying

24
Q

Acarbose MOA

A

Delays digestion of starch and sucrose

25
Repaglinide
Meglitinide
26
Nateglinide
Meglitinide
27
Meglitinide MOA
Increases pancreatic insulin secretion (same as sulfonylureas although with less hypoglycaemia) Not licensed for any other combination other than metformin