Antidotes

Question 1

Antidote for acetaminophen?

Answer 1

N-acetylcysteine to replenish glutathione, atropine

Question 2

Antidote for organophosphates/AChE inhibitors?

Answer 2

Atropine followed by pralidoxime, physostigmine

Question 3

Antidote for atropine/antimuscarinics/anticholinergics?

Answer 3

physostigmine, control hyperthermia

Question 4

Antidote for arsenic, mercury, gold, lead?

Answer 4

dimercaprol + 2,3-dimercaptosuccinic acid (BAL;British anti-lewisite), succimer

Question 5

Antidote for benzodiazipines, zolpidem, zaleplon?

Answer 5

flumazenil

Question 6

Antidote for beta blockers?

Answer 6

glucagon

Question 7

Antidote for carbon monoxide?

Answer 7

100% oxygen, hyperbaric oxygen, methylene blue

Question 8

Antidote for cyanide?

Answer 8

amyl nitrate pearls, sodium nitrate, nitrite+sodium thiosulfate, hydroxocobalamin

Question 9

Antidote for digoxin?

Answer 9

anti-digitalis Fab fragments

Question 10

Antidote for ethylene glycol, methanol?

Answer 10

fomepizole>ethanol drip

Question 11

Antidote for heparin?

Answer 11

protamine sulfate

Question 12

Antidote for iron?

Answer 12

deferoxamine, deferasirox (iron chelators)

Question 13

Antidote for isoniazid?

Answer 13

pyridoxine (vitamin B6)

Question 14

Antidotes for lead?

Answer 14

calcium disodium edetate (EDTA), dimercaprol, penicillamine

Succimer PO for milder poisonings, kids

Question 15

Antidote for nitrites?

Answer 15

methylene blue

Question 16

Antidote for opioids?

Answer 16

naloxone

Question 17

Antidote for phenothiazines?

Answer 17

diphenhydramine, benztropine

Question 18

Antidote for salicylates?

Answer 18

sodium bicarbonate to alkalinize urine, dialysis

Question 19

Antidote for TCAs?

Answer 19

sodium bicarbonate to alkalinize plasma

Question 20

Antidote for warfarin?

Answer 20

Vitamin K, fresh plasma (if active bleeding)

Question 21

Antidote for serotonin syndrome?

Answer 21

cyproheptadine

Question 22

Antidote for amphetamines (basic)?

Answer 22

NH4Cl to acidify urine

Question 23

Antidote for copper (esp. Wilson’s), arsenic, gold, iron, lead, mercury?

Answer 23

Penicillamine

Question 24

Antidote for methemoglobin?

Answer 24

methylene blue, vitamin C

Question 25

Antidote for tPA, streptokinase, urokinase?

Answer 25

aminocaproic acid

Question 26

Antidote for theophylline, beta agonists?

Answer 26

Esmolol

Question 27

Backup for lead poisoning and for Cd, Cr, Co, Mn, Zn?

Answer 27

EDTA

Question 28

Antidote for oral poisonings except Fe, Cn, Li, solvents, mineral acids, or corrosives?

Answer 28

Activated charcoal