Antiemetic Flashcards
What drug class is promethazine in?
Phenothiazines
What is the action of promethazine?
Blocks dopamine receptors
Why do we give promethazine
Prevent I treat n/v associated with surgery, anathema, migraine, chemo, AB’s motion sickness
What are the side effects of promethazine?
Anticholinergic, photosensitivity, drowsiness, confusion
What is the contraindication of promethazine
Sub q admin
What drug class is hydroxyzinein?
Antihistamine
What is the action of hydroxyzine
Blocks acetylcholine in brain
What are the se’s of hydroxyzin?
Anticholonergic, confusion, thicker respiratory secretions, tachycardia
What drug class is ondenastron in?
Serotonin receptor agonists
What is the action of ondanestron
Prevent activation of seratorin receptors
Why do we give ondanestron?
Treat/prevent n/v associated with cancer, chemo, and radiation
What are the se’s of ondanestion
Diarrhea, ha, constipation, fatigue
What drug class is Aprepitant in?
Nevrokinin 1 antagonists
What is the action of aprepitant?
Inhibits signal to brain that causes nausea
Why do we give Aprepitant
Treat n/v with chemo
