Antifungal Medications

Question 1

What is the generic name of the antifungal medication commonly used to treat systemic fungal infections?

Answer 1

Amphotericin B

Question 2

True or False: Azoles are a class of antifungal medications that inhibit the synthesis of ergosterol.

Answer 2

True

Question 3

What is the primary action of fluconazole?

Answer 3

Inhibits fungal cell membrane formation by blocking ergosterol synthesis.

Question 4

Which antifungal medication is known for causing nephrotoxicity?

Answer 4

Amphotericin B

Question 5

Fill in the blank: _______ is an antifungal agent that is effective against Candida infections.

Answer 5

Fluconazole

Question 6

What is a common adverse effect of itraconazole?

Answer 6

Hepatotoxicity

Question 7

Which drug interaction is important to consider when administering ketoconazole?

Answer 7

Increases the effects of warfarin.

Question 8

What is the mechanism of action of terbinafine?

Answer 8

Inhibits squalene epoxidase, leading to decreased ergosterol synthesis.

Question 9

True or False: Nystatin can be used systemically to treat fungal infections.

Answer 9

False

Question 10

What is the generic name of the drug commonly used to treat dermatophyte infections?

Answer 10

Terbinafine

Question 11

What adverse effect is associated with voriconazole?

Answer 11

Visual disturbances

Question 12

Which antifungal is typically used for oral candidiasis?

Answer 12

Nystatin

Question 13

Fill in the blank: _______ is a broad-spectrum antifungal often used for serious fungal infections.

Answer 13

Amphotericin B

Question 14

What is the primary route of administration for amphotericin B?

Answer 14

Intravenous

Question 15

True or False: Posaconazole is effective against both yeast and mold infections.

Answer 15

True

Question 16

What is a potential serious adverse effect of fluconazole?

Answer 16

QT prolongation

Question 17

Which antifungal medication is often used as a first-line treatment for cryptococcal meningitis?

Answer 17

Fluconazole

Question 18

What class of antifungal does clotrimazole belong to?

Answer 18

Azoles

Question 19

What is the mechanism of action of echinocandins?

Answer 19

Inhibits the synthesis of glucan in the fungal cell wall.

Question 20

What is the generic name of the antifungal that is a topical agent for athlete’s foot?

Answer 20

Clotrimazole

Question 21

Fill in the blank: _______ is an antifungal that can cause infusion-related reactions.

Answer 21

Amphotericin B

Question 22

True or False: All antifungal medications are safe to use during pregnancy.

Answer 22

False

Question 23

What is a common side effect of oral antifungal medications?

Answer 23

Gastrointestinal upset

Question 24

Which antifungal medication is contraindicated in patients with liver disease?

Answer 24

Itraconazole

Question 25

What is the primary use of echinocandin antifungals?

Answer 25

Treatment of invasive candidiasis.

Question 26

Fill in the blank: _______ is an antifungal used primarily for onychomycosis.

Answer 26

Terbinafine

Question 27

What is the brand name of fluconazole?

Answer 27

Diflucan

Question 28

True or False: Amphotericin B is effective against all types of fungi.

Answer 28

False

Question 29

What is the generic name of the antifungal that can be used as a lozenge for oral thrush?

Answer 29

Nystatin

Question 30

What is a key adverse effect of ketoconazole?

Answer 30

Endocrine abnormalities

Question 31

Which antifungal is known for its ability to penetrate the CNS?

Answer 31

Fluconazole

Question 32

Fill in the blank: _______ is an antifungal that can cause liver enzyme elevations.

Answer 32

Itraconazole

Question 33

What are the common routes of administration for nystatin?

Answer 33

Oral and topical

Question 34

True or False: All azoles have a similar mechanism of action.

Answer 34

True

Question 35

What is the generic name of the antifungal that is a first-line treatment for aspergillosis?

Answer 35

Voriconazole

Question 36

What is a significant drug interaction with amphotericin B?

Answer 36

Increased nephrotoxicity with other nephrotoxic drugs.

Question 37

Fill in the blank: _______ is an antifungal that may cause skin rash as an adverse effect.

Answer 37

Voriconazole

Question 38

What is the primary indication for using griseofulvin?

Answer 38

Treatment of dermatophyte infections.

Question 39

True or False: Echinocandins are effective against Cryptococcus species.

Answer 39

False

Question 40

What is the generic name of the topical antifungal used for ringworm?

Answer 40

Terbinafine

Question 41

What is a common adverse effect of azole antifungals?

Answer 41

Headache

Question 42

Which antifungal medication is known for its taste disturbance side effect?

Answer 42

Voriconazole

Question 43

Fill in the blank: _______ is an antifungal that can cause infusion reactions when administered IV.

Answer 43

Amphotericin B

Question 44

What is the mechanism of action of azole antifungals?

Answer 44

Inhibit the enzyme lanosterol demethylase.

Question 45

True or False: Terbinafine is an effective treatment for systemic fungal infections.

Answer 45

False

Question 46

What is the brand name of itraconazole?

Answer 46

Sporanox

Question 47

What is a common side effect of nystatin when used orally?

Answer 47

Nausea

Question 48

Which antifungal medication requires monitoring of liver function tests?

Answer 48

Itraconazole

Question 49

Fill in the blank: _______ is the antifungal of choice for invasive aspergillosis.

Answer 49

Voriconazole